Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
CARDIAC EFFECTS OF SUMATRIPTAN - FINDINGS OF HOLTER MONITORING AND REVIEW OF THE LITERATURE
Autore:
WOBER C; WESSELY P; FREY B; MARTERER A; ZEILER K;
Indirizzi:
UNIV VIENNA,DEPT NEUROL,WAEHRINGER GUERTEL 18 A-1090 VIENNA AUSTRIA UNIV VIENNA,DEPT MED 2 A-1090 VIENNA AUSTRIA
Titolo Testata:
Wiener Klinische Wochenschrift
fascicolo: 9, volume: 110, anno: 1998,
pagine: 331 - 337
SICI:
0043-5325(1998)110:9<331:CEOS-F>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRANSMURAL MYOCARDIAL-INFARCTION; CHEST PAIN; SUBCUTANEOUS SUMATRIPTAN; CORONARY VASOSPASM; CLUSTER HEADACHE; MIGRAINE; CIRCULATION; ASSOCIATION; AGONIST; DRUG;
Keywords:
SUMATRIPTAN; CARDIAC ADVERSE EVENTS; ECG HOLTER MONITORING;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
48
Recensione:
Indirizzi per estratti:
Citazione:
C. Wober et al., "CARDIAC EFFECTS OF SUMATRIPTAN - FINDINGS OF HOLTER MONITORING AND REVIEW OF THE LITERATURE", Wiener Klinische Wochenschrift, 110(9), 1998, pp. 331-337

Abstract

The aim of this study was to elucidate possible electrocardiographic effects of sumatriptan in a selected group of patients with severe headache requiring in-patient treatment. The patients (n=21) were treatedwith sumatriptan in addition to various other compounds and were asked to record any symptoms following the administration of sumatriptan. In addition, Hotter monitoring was performed in all subjects. In agreement with other studies, the adverse events reported by the patients were not related to ECG changes and, vice versa, ECG changes were not accompanied by clinical symptoms. The Holter findings before and after administration of sumatriptan were significantly different in three patients, i.e. recurrent episodes of ST depression and in crease in extrasystoles. These changes occurred within a period of 1.45 to 18 hours and were not reproducible when Holter monitoring was repeated without sumatriptan. Even though the findings might be explained by spontaneous variability of Hotter monitoring or other factors, this study does not definitely discount the possibility that sumatriptan may cause ST segment changes and increase pre-existing extrasystoles. Controlled studies are required to clarify this issue.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 18:27:06