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Titolo:
COMPLETE RECOVERY OF RENAL-FUNCTION IN A WILMS-TUMOR PATIENT AFTER ACUTE-RENAL-FAILURE CAUSED BY AUTOLOGOUS BONE-MARROW TRANSPLANTATION (ABMT)
Autore:
HEMPEL L; PATZER L; MISSELWITZ J; FUCHS D; ZINTL F;
Indirizzi:
UNIV JENA,DEPT PEDIAT,KOCHSTR 2 D-07745 JENA GERMANY
Titolo Testata:
Pediatric hematology and oncology
fascicolo: 3, volume: 15, anno: 1998,
pagine: 255 - 260
SICI:
0888-0018(1998)15:3<255:CRORIA>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEPHROBLASTOMA; CHILDREN;
Keywords:
AUTOLOGOUS BONE MARROW TRANSPLANTATION; NEPHROBLASTOMA; NEPHROTOXICITY; WILMS TUMOR;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
10
Recensione:
Indirizzi per estratti:
Citazione:
L. Hempel et al., "COMPLETE RECOVERY OF RENAL-FUNCTION IN A WILMS-TUMOR PATIENT AFTER ACUTE-RENAL-FAILURE CAUSED BY AUTOLOGOUS BONE-MARROW TRANSPLANTATION (ABMT)", Pediatric hematology and oncology, 15(3), 1998, pp. 255-260

Abstract

An autologous bone marrow transplantation (ABMT) was carried out on a4-year-old boy following the second pulmonary relapse of a nephroblastoma. Glomerular and tubular function of the remaining kidney before ABMT was normal. Etoposide, carboplatin, and melphalan were used in theconditioning regimen. The patient developed acute renal failure (ARF), and hemodialysis was required for 3 weeks. The situation was furthercomplicated by his requiring mechanical ventilation for 12 days. Today, the patient is in good general health and in stable remission 32 months after bone marrow transplantation. This report shows that even serious tubular and glomerular dysfunction may be completely reversible in children. The background for high-dose chemotherapy with ABMT or stem cell rescue is discussed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 11:50:48