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Titolo:
MATERNAL IMMUNE-RESPONSE TO HIV-1 AND PERINATAL TRANSMISSION
Autore:
LANDAY AL; SIEGEL JN; RICH K;
Indirizzi:
UNIV ILLINOIS,DEPT PEDIAT,840 SOUTHWOOD ST,MC 856 CHICAGO IL 60612 UNIV ILLINOIS,DEPT PEDIAT CHICAGO IL 60612 RUSH MED COLL,DEPT IMMUNOL MICROBIOL CHICAGO IL 60612
Titolo Testata:
Immunology and allergy clinics of North America
fascicolo: 2, volume: 18, anno: 1998,
pagine: 355 -
SICI:
0889-8561(1998)18:2<355:MITHAP>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN-IMMUNODEFICIENCY-VIRUS; DEPENDENT CELLULAR CYTOTOXICITY; T-LYMPHOCYTE ACTIVITY; TUMOR-NECROSIS-FACTOR; NORMAL HUMAN-PREGNANCY; AIDS-RELATED COMPLEX; VERTICAL TRANSMISSION; PERIPHERAL-BLOOD; SEROPOSITIVE INDIVIDUALS; INTERLEUKIN-4 PRODUCTION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
117
Recensione:
Indirizzi per estratti:
Citazione:
A.L. Landay et al., "MATERNAL IMMUNE-RESPONSE TO HIV-1 AND PERINATAL TRANSMISSION", Immunology and allergy clinics of North America, 18(2), 1998, pp. 355

Abstract

Pregnancy represents a time of dynamic physiologic changes in immunoregulation with a predominant Type 2 immune response. HIV infection during pregnancy impacts the immune system, especially CD4 depletion and cellular activation. How these immune factors ultimately determine maternal-fetal HIV transmission is extremely complex. We are now beginning to understand the immune factors that influence HN transmission, both systemically and at the placental interface. A better understanding of these factors will potentially lead to development of new therapeutic intervention for reducing maternal-fetal HIV transmission.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 17:18:32