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Titolo:
PREDICTORS OF CORTISOL AND 3-METHOXY-4-HYDROXYPHENYLGLYCOL RESPONSES IN THE ACUTE AFTERMATH OF RAPE
Autore:
YEHUDA R; RESNICK HS; SCHMEIDLER J; YANG RK; PITMAN RK;
Indirizzi:
CUNY MT SINAI SCH MED,VET AFFAIRS MED CTR,DEPT PSYCHIAT,130 W KINGSBRIDGE RD BRONX NY 10468 MED UNIV S CAROLINA,DEPT PSYCHIAT & BEHAV SCI CHARLESTON SC 29425 VET ADM MED CTR,RES SERV MANCHESTER NH 00000 HARVARD UNIV,SCH MED BOSTON MA 00000
Titolo Testata:
Biological psychiatry
fascicolo: 11, volume: 43, anno: 1998,
pagine: 855 - 859
SICI:
0006-3223(1998)43:11<855:POCA3R>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSTTRAUMATIC-STRESS-DISORDER; VIETNAM COMBAT VETERANS; URINARY CORTISOL; CATECHOLAMINE EXCRETION; PLASMA-CORTISOL; BRAIN-REGIONS; NOREPINEPHRINE; SUPPRESSION; SECRETION; RAT;
Keywords:
POSTTRAUMATIC STRESS DISORDER; RAPE; CORTISOL; CATECHOLAMINES; 3-METHOXY-4-HYDROXYPHENYLGLYCOL; PRIOR HISTORY; RISK FACTORS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
45
Recensione:
Indirizzi per estratti:
Citazione:
R. Yehuda et al., "PREDICTORS OF CORTISOL AND 3-METHOXY-4-HYDROXYPHENYLGLYCOL RESPONSES IN THE ACUTE AFTERMATH OF RAPE", Biological psychiatry, 43(11), 1998, pp. 855-859

Abstract

Background: Prospective studies of trauma survivors can provide information about the relationship between rape characteristics and the development of subsequent symptoms. Methods: The present study examined the relationship of prior assault, rape severity, posttraumatic stress disorder (PTSD) symptoms following rape, and subsequent PTSD diagnosis, to the acute cortisol and 3-methoxy,-4-hydroxyphenylglycol (MHPG) response to this traumatic event in 20 women. Results: Women with a history of prior physical or sexual assault showed a significantly attenuated cortisol response to the acute stress of rape compared to women without such a history. MHPG appeared to be associated with injury-related rape characteristics, and symptoms of active avoidance, but not prior history. PTSD status at the 3-month follow-up was predicted by botha prior history of assault and high injury rape, but was not directlypredicted by either cortisol or MHPG levels. MHPG and cortisol were nor correlated in the sample as a whole, but were correlated among individuals who did not subsequently develop PTSD (p = .04). Conclusions: The results suggest that different neuroendocrine systems may mediate different components of the response to traumatic stress. Published 1998 Society of Biological Psychiatry.

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Documento generato il 13/07/20 alle ore 16:39:59