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Titolo:
PREPARATION, CHARACTERIZATION, AND EVALUATION OF PHYSICOCHEMICAL PROPERTIES OF DIFFERENT CRYSTALLINE FORMS OF IBUPROFEN
Autore:
KHAN GM; ZHU JB;
Indirizzi:
GOMAL UNIV,FAC PHARM,DERA ISMAIL KHAN PESHAWAR PAKISTAN CHINA PHARMACEUT UNIV,SCH PHARM,ZHONG KUN PHARMACEUT RES INST NANJING210009 PEOPLES R CHINA
Titolo Testata:
Drug development and industrial pharmacy
fascicolo: 5, volume: 24, anno: 1998,
pagine: 463 - 471
SICI:
0363-9045(1998)24:5<463:PCAEOP>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
9
Recensione:
Indirizzi per estratti:
Citazione:
G.M. Khan e J.B. Zhu, "PREPARATION, CHARACTERIZATION, AND EVALUATION OF PHYSICOCHEMICAL PROPERTIES OF DIFFERENT CRYSTALLINE FORMS OF IBUPROFEN", Drug development and industrial pharmacy, 24(5), 1998, pp. 463-471

Abstract

Different crystal forms of ibuprofen (IBF) were prepared using methods such as cooling hot solution of the drug and precipitation of crystals from the drug solution. Scanning electron microscopy (SEM), differential scanning calorimetry (DSC), melting point, x-ray powder diffractometry, infrared absorption spectroscopy (IR), and in vitro dissolution rate and stability studies were conducted to investigate various characteristics of different crystalline forms of the drug. Methods of preparation and nature of the solvents used in this study were found to have greater roles in changing the physicochemical properties of IBF.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 02:52:14