Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
SOLUTION STRUCTURE OF MESOBILIVERDIN XIII-ALPHA BRIDGED BETWEEN THE PROPIONIC-ACID SUBSTITUENTS
Autore:
CRUSATS J; BENITEZ P; FARRERA JA; RUBIRES R; RIBO JM;
Indirizzi:
UNIV BARCELONA,DEPT QUIM ORGAN,DIAGONAL 647 E-08028 BARCELONA SPAIN UNIV BARCELONA,DEPT QUIM ORGAN E-08028 BARCELONA SPAIN
Titolo Testata:
Monatshefte fuer Chemie
fascicolo: 5, volume: 129, anno: 1998,
pagine: 535 - 544
SICI:
0026-9247(1998)129:5<535:SSOMXB>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
MOLECULAR-DYNAMICS SIMULATIONS; PYRROLE PIGMENTS; CHIRAL DISCRIMINATION; BILE-PIGMENTS; IX-ALPHA; BILIVERDIN; BILIPEPTIDES; CHEMISTRY; BILIRUBIN; SPECTRA;
Keywords:
BILE PIGMENTS; INDUCED CIRCULAR DICHROISM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
43
Recensione:
Indirizzi per estratti:
Citazione:
J. Crusats et al., "SOLUTION STRUCTURE OF MESOBILIVERDIN XIII-ALPHA BRIDGED BETWEEN THE PROPIONIC-ACID SUBSTITUENTS", Monatshefte fuer Chemie, 129(5), 1998, pp. 535-544

Abstract

The solution structure of two intramolecular diesters (methylene and 1,3-propylidene) of mesobiliverdin-XIII alpha was studied and comparedwith that of the corresponding dimethyl ester. The UV/Vis absorption spectra, chiral discrimination with ethyl (S)-(-)-lactate, and the H-1NMR spectra (ROESY) show that the cyclization of the propionate substituents of biliverdins does not significantly affect the helix structure or its (P) reversible arrow (M) interconversion. The internal methylene diester does not show conformational heterogeneity of the propionate substituents and probably exists only in one diastereomeric form. In this case, the results point to a simultaneous racemization of the tetrapyrrole helix and the bridge cycle. The methylene diester of mesoprotoporphyrin was also synthesized. In this case, the geometry of thepropionate chains is probably similar to that present in some hemoproteins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/09/20 alle ore 13:15:42