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Titolo:
EFFECTS OF BALLOON ANGIOPLASTY AND STENT IMPLANTATION ON INTRARENAL ECHO-DOPPLER VELOCIMETRIC INDEXES
Autore:
MARANA I; AIROLDI F; BURDICK L; ALBERTI C; LOVARIA A; SACCHERI S; GAZZANO G; PALATRESI S; NADOR B; TUROLO L; MORGANTI A;
Indirizzi:
UNIV MILAN,CTR FISIOL CLIN & IPERTENS,VIA F SFORZA 35 I-20122 MILAN ITALY UNIV MILAN,CTR FISIOL CLIN & IPERTENS I-20122 MILAN ITALY UNIV MILAN,IST CLIN MED GEN & TERAPIA MED I-20122 MILAN ITALY OSPED MAGGIORE,IRCCS,SERV RADIOL MILAN ITALY
Titolo Testata:
Kidney international
fascicolo: 6, volume: 53, anno: 1998,
pagine: 1795 - 1800
SICI:
0085-2538(1998)53:6<1795:EOBAAS>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
RENAL-ARTERY STENOSIS; ANGIOTENSIN-CONVERTING ENZYME; RENOVASCULAR DISEASE; US EVALUATION; INDEX; ACCELERATION; HYPERTENSION; PULSATILITY; INHIBITION; CAPTOPRIL;
Keywords:
ATHEROSCLEROTIC STENOSIS; FIBROMUSCULAR RENAL ARTERY STENOSIS; PLASMA RENIN ACTIVITY; ANGIOTENSIN II;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
I. Marana et al., "EFFECTS OF BALLOON ANGIOPLASTY AND STENT IMPLANTATION ON INTRARENAL ECHO-DOPPLER VELOCIMETRIC INDEXES", Kidney international, 53(6), 1998, pp. 1795-1800

Abstract

This study was aimed at examining whether four intrarenal echo-Doppler velocimetric indices (pulsatility and resistive indices, acceleration and acceleration time) can be useful for assessing the effects of renal artery dilation obtained with either angioplasty or stent implantation. Echo-Doppler studies were performed in 63 hypertensive patients with 68 renal artery stenoses (39 atherosclerotic and 29 fibromuscular) prior to and within five days after the dilation procedures (55 angioplasties, 13 stent implantations), which resulted in an average reduction of arterial narrowing from 79% to 20%. In 24 patients, the velocimetric indices were also examined in relationship to the venoarterial differences of plasma renin activity and of angiotensin II across the stenotic kidneys. We found that after dilation the values of the four indices had returned within the normal range in all but three arteries(one false negative for resistive index and two for acceleration time). However, decrements in acceleration time was the only factor to be significantly correlated with the reduction of arterial narrowing. Moreover, post-dilation values of this index were, on average, slightly but significantly higher in arteries that at follow-up developed restenosis rather than in those that remained patent. For similar reductionsin arterial narrowing the absolute changes of all indices were similar in atherosclerotic and fibromuscular stenotic arteries and, in a subset of the atheromatous arteries, were also similar after angioplasty and stent implantation. No relationship was found with the changes in the venoarterial differences of plasma renin activity and angiotensin II. It appears that these intrarenal velocimetric indices and, in particular, acceleration time reliably reflect the technical success of renal artery dilation. The acceleration time index may also be valuable for predicting the restenosis of the dilated vessel. None of the indices, however, mirrors the functional consequences of removal of renal artery stenosis as expressed through the changes in transrenal gradients of the components of the renin-angiotensin system.

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Documento generato il 04/12/20 alle ore 00:33:35