Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
HIGH DELTA-SLEEP-INDUCING PEPTIDE-LIKE IMMUNOREACTIVITY IN PLASMA IN SUICIDAL PATIENTS WITH MAJOR DEPRESSIVE DISORDER
Autore:
WESTRIN A; EKMAN R; TRASKMANBENDZ L;
Indirizzi:
UNIV LUND HOSP,DEPT PSYCHIAT S-22185 LUND SWEDEN LUND UNIV,DEPT CLIN NEUROSCI,DIV PSYCHIAT LUND SWEDEN UNIV GOTHENBURG,SECT PSYCHIAT & NEUROCHEM,DEPT NEUROSCI GOTHENBURG SWEDEN
Titolo Testata:
Biological psychiatry
fascicolo: 10, volume: 43, anno: 1998,
pagine: 734 - 739
SICI:
0006-3223(1998)43:10<734:HDPIIP>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORTISOL SECRETION; ACTH; DSIP; BEHAVIOR; STRESS; SCALE; CRH;
Keywords:
SUICIDE ATTEMPT; MAJOR DEPRESSION; DEXAMETHASONE; DELTA SLEEP-INDUCING PEPTIDE; CORTISOL; HYPOTHALAMIC-PITUITARY-ADRENAL AXIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
A. Westrin et al., "HIGH DELTA-SLEEP-INDUCING PEPTIDE-LIKE IMMUNOREACTIVITY IN PLASMA IN SUICIDAL PATIENTS WITH MAJOR DEPRESSIVE DISORDER", Biological psychiatry, 43(10), 1998, pp. 734-739

Abstract

Background: Delta sleep-inducing peptide (DSIP) supposedly involves the hypothalamus-pituitary-adrenal (HPA) axis. Previous studies have shown deviated plasma DSIP-like immunoreactivity (DSIP-LI) levels, as well as abnormal DSIP-LIW responses to corticotropin-releasing hormone in patients with major depressive disorder (MDD). This study was performed to investigate plasma-DSIP-LI and its association with the dexamethasone suppression test (DST) in suicide attempters. Methods: Plasma-DSIP and serum cortisol were measured before and after dexamethasone intake in 34 suicide attempters and in healthy age-and sex-matched controls. Results: We Sound significantly elevated DSIP-LI levels in MDD patients (p < .005), and a significant correlation between predexamethasone cortisol and predexamethasone DSIP-LI levels in healthy controls, Postdexamethasone DSIP-LI levels increased in subjects with low predexamethasone DSIP-LI levels, whereas they decreased in subjects with high predexamethasone DSIP-LI levels. Conclusions: Results give some support to the theory of glucocorticoid involvement in the regulation of DSIP, and suggest altered DSIP-LI levels in suicidal MDD patients. (C) 1998 Society of Biological Psychiatry.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/01/20 alle ore 15:13:00