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Titolo:
COMBINATION THERAPY IN ONCOLOGY (MULTIMOD AL TREATMENT) - PANCREAS TUMORS
Autore:
IHSE I; ANDERSSON R; AXELSON J; HANSSON L;
Indirizzi:
UNIV LUND HOSP,DEPT SURG S-22185 LUND SWEDEN
Titolo Testata:
Chirurg
fascicolo: 4, volume: 69, anno: 1998,
pagine: 366 - 370
SICI:
0009-4722(1998)69:4<366:CTIO(A>2.0.ZU;2-7
Fonte:
ISI
Lingua:
GER
Soggetto:
INTRAOPERATIVE RADIATION-THERAPY; PREOPERATIVE CHEMORADIATION; CURATIVE RESECTION; CANCER; ADENOCARCINOMA; CARCINOMA; HEAD; SURVIVAL; ADJUVANT; PANCREATICODUODENECTOMY;
Keywords:
ADENOCARCINOMA; CHEMOTHERAPY; PANCREAS; RADIOTHERAPY; SURGERY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
37
Recensione:
Indirizzi per estratti:
Citazione:
I. Ihse et al., "COMBINATION THERAPY IN ONCOLOGY (MULTIMOD AL TREATMENT) - PANCREAS TUMORS", Chirurg, 69(4), 1998, pp. 366-370

Abstract

The majority of patients with pancreatic cancer have systemic diseasealready at diagnosis, and nearly all patients will develop recurrencefollowing radical resection. Thus, surgical treatment alone is insufficient. The paper focuses on adjuvant multimodal treatment and reviewsthe current status of pre-and postoperative chemoradiation, intraoperative radiotherapy (IORT), adjuvant chemotherapy, and regional infusion therapy. Studies in this area are hampered by often being nonrandomized and with too few patients included. Overall there presently is no adjuvant multimodal treatment which can be suggested for routine use. However, two ongoing prospective randomized studies (ESPAC-1 and an EORTC study) will have enough statistical power to give reliable information on the topic. It is hoped that these and other studies will form the basis for further proper clinical trials on multimodal treatment in pancreatic cancer with the aim at long last to improve the extremelypoor survival in these patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 14:47:23