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Titolo:
NONINVASIVE ANALYSIS OF RENAL-ARTERY BLOOD-FLOW DYNAMICS WITH MR CINEPHASE-CONTRAST FLOW MEASUREMENTS
Autore:
SCHOENBERG SO; JUST A; BOCK M; KNOPP MV; PERSSON PB; KIRCHHEIM HR;
Indirizzi:
UNIV HEIDELBERG,INST PHYSIOL 1,NEUENHEIMER FELD 326 D-69120 HEIDELBERG GERMANY UNIV HEIDELBERG,INST PHYSIOL 1 D-69120 HEIDELBERG GERMANY DEUTSCH KREBSFORSCHUNGSZENTRUM,FORSCH SCHWERPUNKT RADIOL DIAGNOST & THERAPIE D-69120 HEIDELBERG GERMANY HUMBOLDT UNIV BERLIN,INST PHYSIOL D-10117 BERLIN GERMANY
Titolo Testata:
American journal of physiology. Heart and circulatory physiology
fascicolo: 5, volume: 41, anno: 1997,
pagine: 2477 - 2484
SICI:
0363-6135(1997)41:5<2477:NAORBD>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
DOWNSTREAM CIRCULATION; SLOWED SYSTOLE; STENOSIS; SONOGRAPHY; TARDUS;
Keywords:
MAGNETIC RESONANCE; FLOW PULSE; FLOW ANALYSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
S.O. Schoenberg et al., "NONINVASIVE ANALYSIS OF RENAL-ARTERY BLOOD-FLOW DYNAMICS WITH MR CINEPHASE-CONTRAST FLOW MEASUREMENTS", American journal of physiology. Heart and circulatory physiology, 41(5), 1997, pp. 2477-2484

Abstract

It was the aim of this study to quantify the measurement of pulsatileflow in the renal artery with the noninvasive magnetic resonance cinephase-contrast (MRCPC) method and combine it with the simultaneous assessment of pulsatile flow with a transit-time ultrasound (TTUS) flowmeter. In seven foxhounds with a chronically implanted precalibrated TTUS flow probe, MRCPC flow measurements were made in the renal artery with a temporal resolution of 32 ms. Mean and pulsatile flow signals were compared by the simultaneous ipsi- or contralateral measurement of the renal blood flow signal by both methods (TTUS and MRCPC). In addition, comparative MRCPC and TTUS flow measurements were made with artificial renal artery stenosis and after the administration of angiotensin II. The mean flow data assessed by the noninvasive MRCPC flow measurements showed an excellent correlation with the corresponding TTUS recordings (r = 0.99). The MRCPC flow signal displayed a waveform of the renal artery flow profile that was very similar to the TTUS flow pulse. The hemodynamic changes induced by angiotensin II or due to renal artery stenosis were also reliably detected by MRCPC. MRCPC provides a reliable noninvasive method for the quantification of mean blood flow and the assessment of the pulsatile flow signal in the renal artery andproves to be sensitive to hemodynamic changes of pathophysiological importance. Alternatively, the method may be used for studies in physiology that demand a noninvasive approach.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/09/20 alle ore 11:10:00