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Titolo:
MODELING OF ARTERIAL AND CARDIOPULMONARY BAROREFLEX CONTROL OF HEART-RATE
Autore:
DESAI TH; COLLINS JC; SNELL M; MOSQUEDAGARCIA R;
Indirizzi:
VANDERBILT UNIV SCH MED,CLIN RES CTR,AA3228 MED CTR N NASHVILLE TN 37232 VANDERBILT UNIV,DEPT BIOMED ENGN NASHVILLE TN 37232 VANDERBILT UNIV,DEPT MED NASHVILLE TN 37232 VANDERBILT UNIV,DEPT PHARMACOL NASHVILLE TN 37232
Titolo Testata:
American journal of physiology. Heart and circulatory physiology
fascicolo: 5, volume: 41, anno: 1997,
pagine: 2343 - 2352
SICI:
0363-6135(1997)41:5<2343:MOAACB>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
BODY NEGATIVE-PRESSURE; BARORECEPTOR REFLEX; CAROTID BAROREFLEX; STEADY-STATE; RESPONSES; REGRESSION; HUMANS;
Keywords:
BLOOD PRESSURE; BARORECEPTOR; R-R INTERVAL; VASOACTIVE DRUGS; NECK CHAMBER;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
32
Recensione:
Indirizzi per estratti:
Citazione:
T.H. Desai et al., "MODELING OF ARTERIAL AND CARDIOPULMONARY BAROREFLEX CONTROL OF HEART-RATE", American journal of physiology. Heart and circulatory physiology, 41(5), 1997, pp. 2343-2352

Abstract

We evaluated R-R interval changes (Delta R-R interval) in 13 subjects(27 +/- 6 yr; 7 men and 6 women) as a function of blood pressure changes at the carotid sinus and aortic arch and central venous pressure changes at the cardiopulmonary receptors. Neck chamber pressure and suction were used to change pressure at the carotid sinus while lower body negative pressure, phenylephrine infusion, and nitroprusside infusion were used to change pressure at the carotid sinus (Delta CSP), aortic arch (Delta AAP), and cardiopulmonary receptors (Delta CPP). Random effects regression analysis showed a significant linear relationship for Delta R-R interval (-1.75 + 1.64 Delta CSP + 15.40 Delta AAP + 29.02 Delta CPP + error), and the correlation (r) between the observed andpredicted Delta R-R interval was 0.82 (P < 0.00001). Sixty-seven percent of the Delta R-R interval variability observed in the study is explained by the model. Delta AAP accounts for similar to 63%, Delta CSP for 14%, and Delta CPP for 23% of the explained Delta R-R interval.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/12/20 alle ore 12:53:15