Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
A MYB HOMOLOG, ATR1, ACTIVATES TRYPTOPHAN GENE-EXPRESSION IN ARABIDOPSIS
Autore:
BENDER J; FINK GR;
Indirizzi:
JOHNS HOPKINS UNIV,SCH PUBL HLTH,DEPT BIOCHEM,615 N WOLFE ST BALTIMORE MD 21205 MIT,WHITEHEAD INST BIOMED RES,CAMBRIDGE CTR 9 CAMBRIDGE MA 02142
Titolo Testata:
Proceedings of the National Academy of Sciences of the United Statesof America
fascicolo: 10, volume: 95, anno: 1998,
pagine: 5655 - 5660
SICI:
0027-8424(1998)95:10<5655:AMHAAT>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
SYNTHASE BETA-SUBUNIT; MESSENGER-RNA; TRANSCRIPTIONAL ACTIVATORS; THALIANA; MUTANTS; RESISTANCE; BIOSYNTHESIS; TRANSLATION; METABOLISM; PRODUCTS;
Keywords:
MYB TRANSCRIPTION FACTOR; TRANSLATIONAL CONTROL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
J. Bender e G.R. Fink, "A MYB HOMOLOG, ATR1, ACTIVATES TRYPTOPHAN GENE-EXPRESSION IN ARABIDOPSIS", Proceedings of the National Academy of Sciences of the United Statesof America, 95(10), 1998, pp. 5655-5660

Abstract

In Arabidopsis thaliana, tryptophan pathway genes are induced in response to starvation, wounding, and pathogen attack, resulting in increased production of tryptophan and secondary metabolites important for development and defense. The Arabidopsis tryptophan pathway therefore provides an ideal system for elucidating how environmental stimuli are transduced into changes in plant gene expression. To characterize the factors that regulate the first gene in the pathway, ASA1, which is the key point of control, eve have isolated altered tryptophan regulation (atr) mutants with deregulated expression of ASA1, One of these mutants, atr1D is dominant for increased transcription of ASA1 in specificseedling tissues. We have used atr1D to clone the ATR1 gene based on its map position. ATR1 encodes a Myb-like transcription factor that modulates ASA1 expression. The ATR1 transcript also includes a 5' regulatory region with three short ORFs, one of which is prematurely terminated by the atr1D mutation, Thus, ATR1 defines the first characterized tryptophan gene regulator in plants, and the atr1D mutation defines a sequence important for ATR1 expression.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/01/21 alle ore 21:29:46