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Titolo:
SEROTONIN-1B AGONISTS INDUCE COMPARTMENTALLY ORGANIZED STRIATAL FOS EXPRESSION IN RATS
Autore:
WIRTSHAFTER D; COOK DF;
Indirizzi:
UNIV ILLINOIS,DEPT PSYCHOL,M-C 285,1007 W HARRISON ST CHICAGO IL 60607
Titolo Testata:
NeuroReport
fascicolo: 6, volume: 9, anno: 1998,
pagine: 1217 - 1221
SICI:
0959-4965(1998)9:6<1217:SAICOS>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
GENE C-FOS; RECEPTOR AGONIST; ACTIVATION; DOPAMINE; COCAINE; BRAIN; ANPIRTOLINE; AMPHETAMINE; IMMUNOREACTIVITY;
Keywords:
ANPIRTOLINE; C-FOS; 5-MT1B RECEPTOR; IMMEDIATE EARLY GENES; RU24969; SEROTONIN; STRIATUM; STRIOSOMES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
D. Wirtshafter e D.F. Cook, "SEROTONIN-1B AGONISTS INDUCE COMPARTMENTALLY ORGANIZED STRIATAL FOS EXPRESSION IN RATS", NeuroReport, 9(6), 1998, pp. 1217-1221

Abstract

THE 5HT(1B) agonists RU24969 (2.5-5.0 mg/kg) and anpirtoline (2.0 mg/kg) induced a striking increase in striatal Fos-like immunoreactivity in rats. In the rostral and dorsal regions of the striatum staining was dense and relatively homogeneous. In the ventral region of the striatum at more caudal levels, however, both drugs induced staining in patches which were in register with the opiate receptor rich striosomes. The effects of RU24969 could not be antagonized by the selective 5HT(1A) antagonist p-MPPI and little or no striatal Fos expression could beobserved after injections of the selective 5HT(1A) agonist 8-OHDPAT or the selective 5HT3 antagonist MDL-72222. (C) 1998 Rapid Science Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/09/20 alle ore 05:04:03