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Titolo:
NONINVASIVE MAPPING OF PLACENTAL PERFUSION
Autore:
FRANCIS ST; DUNCAN KR; MOORE RJ; BAKER PN; JOHNSON IR; GOWLAND PA;
Indirizzi:
UNIV NOTTINGHAM,DEPT PHYS,MAGNET RESONANCE CTR NOTTINGHAM NG7 2RD ENGLAND UNIV NOTTINGHAM,DEPT PHYS,MAGNET RESONANCE CTR NOTTINGHAM NG7 2RD ENGLAND CITY HOSP,DEPT OBSTET & GYNAECOL NOTTINGHAM NG5 1PB ENGLAND
Titolo Testata:
Lancet
fascicolo: 9113, volume: 351, anno: 1998,
pagine: 1397 - 1399
SICI:
0140-6736(1998)351:9113<1397:NMOPP>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLANAR MAGNETIC-RESONANCE; FETAL GROWTH-RETARDATION; PREGNANCY; WEIGHT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
12
Recensione:
Indirizzi per estratti:
Citazione:
S.T. Francis et al., "NONINVASIVE MAPPING OF PLACENTAL PERFUSION", Lancet, 351(9113), 1998, pp. 1397-1399

Abstract

Background. We aim to develop a clinical technique for the non-invasive measurement of placental perfusion, to enable early detection of intrauterine growth restriction (IUGR). Pregnancies with this complication are characterised by low placental perfusion. Methods. We measured placental perfusion by means of perfusion-sensitive echoplanar imaging(EPI); a rapid method of making magnetic resonance images. Perfusion measurements were done on six healthy volunteers with normal pregnancies and nine with pregnancies complicated by IUGR. Perfusion maps were created to assess the relation between placental perfusion and fetal size at birth. Findings. Pregnancies complicated by IUGR differed significantly from normal pregnancies in patterns of perfusion within the placenta (p < 0.0001, ANOVA). Subsequent analysis showed that the proportion of placentas with low perfusion rates was higher in the IUGR group than in the normal group. A significant correlation between areas of reduced placental perfusion and fetal size was demonstrated (p = 0.041, Spearman's rank correlation). Interpretation. Non-invasive imagingof placental perfusion by means of EPI has potential as a clinical tool in assessing the dynamics of placental perfusion.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 18:15:24