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Titolo:
ALTERED CEREBRAL ENERGY-UTILIZATION IN LATE-LIFE DEPRESSION
Autore:
COOK IA; LEUCHTER AF; UIJTDEHAAGE SHJ; OSATO S; HOLSCHNEIDER DH; ABRAMS M; ROSENBERGTHOMPSON S;
Indirizzi:
UNIV CALIF LOS ANGELES,SCH MED,NEUROPSYCHIAT INST & HOSP,QUANTITAT EEG LAB LOS ANGELES CA 90024 UNIV CALIF LOS ANGELES,SCH MED,DEPT PSYCHIAT & BIOBEHAV SCI LOS ANGELES CA 00000 VET ADM MED CTR LOS ANGELES CA 00000 UNIV SO CALIF,SCH MED,DEPT PSYCHIAT LOS ANGELES CA 00000 UNIV SO CALIF,SCH MED,DEPT NEUROL LOS ANGELES CA 00000
Titolo Testata:
Journal of affective disorders
fascicolo: 2, volume: 49, anno: 1998,
pagine: 89 - 99
SICI:
0165-0327(1998)49:2<89:ACEILD>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; BLOOD-FLOW; GLUCOSE-METABOLISM; MAJOR DEPRESSION; MOOD DISORDERS; UNIPOLAR DEPRESSION; PERFUSION; EMOTION; CORTEX; STATE;
Keywords:
MAJOR DEPRESSION; LATE LIFE DEPRESSION; PHYSIOLOGY; EEG; CORDANCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
45
Recensione:
Indirizzi per estratti:
Citazione:
I.A. Cook et al., "ALTERED CEREBRAL ENERGY-UTILIZATION IN LATE-LIFE DEPRESSION", Journal of affective disorders, 49(2), 1998, pp. 89-99

Abstract

Background: Global and regional changes in cerebral energy utilization are reported to characterize late life depression. Methods: Twenty seven subjects with late life depression (9 prior to starting medication, 18 after starting) and 27 matched controls were evaluated with cordance, a quantitative EEG measure that reflects cerebral energy utilization. Results: Global and focal (anterior and centrotemporal) differences were present in theta-band cordance between unmedicated depressed and control subjects. Depressed subjects receiving treatment had cordance patterns similar to controls. Conclusions: The presence of both diffuse and focal disturbances in energy utilization prior to initiatingtreatment indicates that cordance detects altered cerebral physiologyin depressed patients, and that this measure may also be sensitive totreatment interventions. (C) 1998 Elsevier Science B.V.

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Documento generato il 28/03/20 alle ore 09:52:20