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Titolo:
SEASONAL DISTRIBUTION OF ACUTE MYOCARDIAL-INFARCTION IN THE 2ND NATIONAL REGISTRY OF MYOCARDIAL-INFARCTION
Autore:
SPENCER FA; GOLDBERG RJ; BECKER RC; GORE JM;
Indirizzi:
UNIV MASSACHUSETTS,MED CTR,DIV CARDIOVASC MED,CARDIOTHROMBOSIS RES CTR,DEPT MED,55 LAKE AVE N WORCESTER MA 01655
Titolo Testata:
Journal of the American College of Cardiology
fascicolo: 6, volume: 31, anno: 1998,
pagine: 1226 - 1233
SICI:
0735-1097(1998)31:6<1226:SDOAMI>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
SUDDEN CARDIAC DEATH; CIRCADIAN VARIATION; DEPRESSED-PATIENTS; BLOOD-PRESSURE; ENVIRONMENTAL-TEMPERATURE; IMIPRAMINE BINDING; PHYSICAL EXERTION; CORONARY-DISEASE; SEROTONIN UPTAKE; UNITED-STATES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
57
Recensione:
Indirizzi per estratti:
Citazione:
F.A. Spencer et al., "SEASONAL DISTRIBUTION OF ACUTE MYOCARDIAL-INFARCTION IN THE 2ND NATIONAL REGISTRY OF MYOCARDIAL-INFARCTION", Journal of the American College of Cardiology, 31(6), 1998, pp. 1226-1233

Abstract

Objectives. This observational study sought to determine whether cases of acute myocardial infarction (AMI) reported to the second NationalRegistry of Myocardial Infarction (NRMI-2) varied by season. Background, The existence of circadian variation in the onset of AMT is well established. Examination of this periodicity has led to new insights into pathophysiologic triggers of atherosclerotic plaque rupture. Although a seasonal pattern for mortality from AMI has been previously noted, it remains unclear whether the occurrence of AMI also displays a seasonal rhythmicity, Documentation of such a pattern may foster investigation of new pathophysiologic determinants of plaque rupture and intracoronary thrombosis. Methods. We analyzed the number of cases of AMI reported to NRMI-2 by season during the period July 1, 1994 to July 31,1996, Data were normalized so that seasonal occurrence of AMI was reported according to a standard 90-day length. Results. A total of 259,891 cases of AMI were analyzed during the study period. Approximately 53% more cases were reported in winter than during the summer. The sameseasonal pattern (decreasing occurrence of reported cases from winterto fall to spring to summer) was seen in men and women, in different age groups and in 9 of 10 geographic areas. In-hospital case fatality rates for AMI also followed a seasonal pattern, with a peak of 9% in winter, Conclusions. The present results suggest that there is a seasonal pattern in the occurrence of AMIs reported to NRMI-2 that is characterized by a marked peak of cases in the winter months and a nadir in the summer months. This pattern was seen in all subgroups analyzed as well as in different geographic areas. These findings suggest that thechronobiology of seasonal variation in AMI may be affected by variables independent of climate.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 06:19:47