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Titolo:
ACUTE CORONARY SYNDROMES IN THE UNITED-STATES AND UNITED-KINGDOM - A COMPARISON OF APPROACHES
Autore:
ADAMS PC; SKINNER JS; COHEN M; MCBRIDE R; FUSTER V;
Indirizzi:
ALLEGHENY UNIV HOSP,DIV CARDIOL,MAIL STOP 119,BROAD & VINE ST PHILADELPHIA PA 19102 ALLEGHENY UNIV HOSP,DIV CARDIOL PHILADELPHIA PA 19102 ROYAL VICTORIA INFIRM,DEPT CARDIOL NEWCASTLE TYNE NE1 4LP TYNE & WEARENGLAND STAT & EPIDEMIOL RES CORP SEATTLE WA 00000 MT SINAI HOSP,DIV CARDIOL NEW YORK NY 10029
Titolo Testata:
Clinical cardiology
fascicolo: 5, volume: 21, anno: 1998,
pagine: 348 - 352
SICI:
0160-9289(1998)21:5<348:ACSITU>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; UNSTABLE ANGINA; ASPIRIN USERS; MANAGEMENT; DISEASE; CANADA; TRIAL; REST;
Keywords:
UNSTABLE ANGINA; UNITED STATES; UNITED KINGDOM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
P.C. Adams et al., "ACUTE CORONARY SYNDROMES IN THE UNITED-STATES AND UNITED-KINGDOM - A COMPARISON OF APPROACHES", Clinical cardiology, 21(5), 1998, pp. 348-352

Abstract

Background: Patients with coronary artery disease are managed differently in different countries. Hypothesis: These variations in patient management may affect clinical outcome, a possibility that should be taken into consideration in multicenter studies. Methods: In a binational, 3 months study of antithrombotic treatment of patients with unstable angina and non-Q-wave infarction (ATACS), we compared the experiencein the four enrollment centers in the United States (US) with the three centers in the United Kingdom (UK). The 59 US patients and the 299 UK patients were similar with regard to age, rates of prior revascularization, prior positive exercise tests, medication use, and aspirin use. Results: US patients were more commonly women (45 vs. 28%), diabetic (30 vs. 4%), or hypertensive (52 vs. 31%), and had a prior coronary angiogram (30 vs. 18%). After enrollment, coronary angiography was performed more frequently in the US than in the UK (61 vs. 22%). Althoughthe distribution of coronary disease was similar, revascularization without recurrent angina (19 vs. 4%, p < 0.001), or following recurrentangina (8 vs. 3%), was significantly more frequent in the US. Combined primary end points (recurrent angina, myocardial infarction, or death) did not differ between US (29%) and UK (25%) patients. Conclusion: Therefore, international studies of acute coronary disease need to account for different treatments in different countries. These differences, in the small ATACS study, did not have a major impact on the composite primary outcome variables.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 00:52:06