Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
CHARACTERISTIC RESPONSE TO TRANSCRANIAL MAGNETIC STIMULATION IN RETT-SYNDROME
Autore:
NEZU A; KIMURA S; TAKESHITA S; TANAKA M;
Indirizzi:
YOKOHAMA CITY UNIV,SCH MED,DEPT PEDIAT,URAFUNE HOSP,MINAMI KU,3-46 URAFUNE CHO YOKOHAMA KANAGAWA 232 JAPAN
Titolo Testata:
ELECTROMYOGRAPHY AND MOTOR CONTROL-ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
fascicolo: 2, volume: 109, anno: 1998,
pagine: 100 - 103
SICI:
0924-980X(1998)109:2<100:CRTTMS>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORTICAL EXCITABILITY; PARKINSONS-DISEASE; MOTOR CORTEX;
Keywords:
RETT SYNDROME; TRANSCRANIAL MAGNETIC STIMULATION; MOTOR CORTICAL EXCITABILITY; CENTRAL MOTOR CONDUCTION TIME;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
A. Nezu et al., "CHARACTERISTIC RESPONSE TO TRANSCRANIAL MAGNETIC STIMULATION IN RETT-SYNDROME", ELECTROMYOGRAPHY AND MOTOR CONTROL-ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 109(2), 1998, pp. 100-103

Abstract

To pathophysiologically evaluate the corticospinal tracts (CSTs) in Rett syndrome (RS), transcranial magnetic stimulation (TMS) was performed in 3 patients aged 4, 6 and 13 years. The two younger cases exhibited the clinical characteristics of the pseudostationary stage (stage III), while ambulation was lost in the oldest case at the age of 11 years (stage IV). The motor cortex and cervical spinal roots were magnetically stimulated to obtain motor evoked potentials (MEPs) from the relaxed first dorsal interosseous muscle. Compared with the central motorconduction time (CMCT) in age-matched normal children, CMCT in the stage III cases was significantly short (6.9-7.1 ms, P < 0.05). In the stage IV case, CMCT was markedly short but not significantly so (6.6 ms, P = 0.06), which was partly due to a significant increase in the threshold intensity of TMS (100%, P < 0.05). Thus, the CMCT shortening, which implied unique cortical hyperexcitability, was considered consistent and characteristic of RS. The CSTs in the stage IV case were certainly impaired, corresponding well to the progressive spastic paresis. (C) 1998 Elsevier Science Ireland Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/01/20 alle ore 16:20:51