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Titolo: PREDICTING PROBABILITIES OF PREGNANCY AND MULTIPLE GESTATION FROM INVITRO FERTILIZATION  A NEW MODEL
Autore: WHEELER CA; COLE BF; FRISHMAN GN; SEIFER DB; LOVEGREEN SB; HACKETT RJ;
 Indirizzi:
 BROWN UNIV,WOMEN & INFANTS HOSP,DEPT OBSTET & GYNECOL,101 DUDLEY ST PROVIDENCE RI 02905 BROWN UNIV,DIV APPL MATH PROVIDENCE RI 02912 OHIO STATE UNIV,MED CTR,DEPT OBSTET & GYNECOL COLUMBUS OH 43210
 Titolo Testata:
 Obstetrics and gynecology
fascicolo: 5,
volume: 91,
anno: 1998,
parte:, 1
pagine: 696  700
 SICI:
 00297844(1998)91:5<696:PPOPAM>2.0.ZU;2R
 Fonte:
 ISI
 Lingua:
 ENG
 Soggetto:
 INVITRO FERTILIZATION; MATERNAL AGE; EMBRYOS; NUMBER; RATES;
 Tipo documento:
 Article
 Natura:
 Periodico
 Settore Disciplinare:
 Science Citation Index Expanded
 Citazioni:
 18
 Recensione:
 Indirizzi per estratti:



 Citazione:
 C.A. Wheeler et al., "PREDICTING PROBABILITIES OF PREGNANCY AND MULTIPLE GESTATION FROM INVITRO FERTILIZATION  A NEW MODEL", Obstetrics and gynecology, 91(5), 1998, pp. 696700
Abstract
Objective: To develop a statistical model that adjusts for variation between patients and adequately predicts the observed distribution of pregnancies among singletons and multiple gestations of various orders. Methods: All in vitro fertilization (IVF) cycles from the inception of the IVF program at Women and Infants' Hospital on May 26, 1988, until December 31, 1993, were evaluated using logistic regression in selected subsets. Results: A new cycleone specific model uses three different probabilities: P1, the probability of pregnancy (predicted by ageand total embryo score); P2\P1, the conditional probability of finding a second implantation in those who had become pregnant with at leastone (predicted by total embryo score); and P3\P2, the conditional probability of finding a third implantation in those who had become pregnant with at least two (with no significant predictors). This is the first model to use these three adjusted probabilities. Conclusion: P1 increases with increasing total embryo score but decreases with increasing age. P2\P1 increases with increasing total embryo score but does not depend on age. Embryo scoring is useful because the total embryo score is a better predictor of P1 and F2\P1 than the number of embryos alone. By using patientspecific information (age and total embryo score) and cyclespecific tables, an estimate of the probability of pregnancy and multiple gestation can be provided before embryo transfer. (C) 1998 by The American College of Obstetricians and Gynecologists.
ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/11/20 alle ore 13:26:07