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Titolo:
EFFECTS OF THALAMIC HEMORRHAGE ON CORTICAL HEMODYNAMIC PARAMETERS ASSESSED BY PERFUSION MR-IMAGING - PRELIMINARY-REPORT
Autore:
BERTHEZENE Y; NIGHOGHOSSIAN N; DAMIEN J; DEREX L; TROUILLAS P; FROMENT JC;
Indirizzi:
HOP NEUROCARDIOL,DEPT RADIOL,CREATIS UMR CNRS 5515,59 BD PINEL F-69003 LYON FRANCE NEUROL HOSP,DEPT NUCL MED LYON FRANCE
Titolo Testata:
Journal of the neurological sciences
fascicolo: 1, volume: 157, anno: 1998,
pagine: 67 - 72
SICI:
0022-510X(1998)157:1<67:EOTHOC>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBRAL BLOOD-FLOW; CONTINUOUS-INHALATION; METABOLISM; TOMOGRAPHY; NEGLECT;
Keywords:
PERFUSION; MRI; THALAMIC HEMORRHAGE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
Y. Berthezene et al., "EFFECTS OF THALAMIC HEMORRHAGE ON CORTICAL HEMODYNAMIC PARAMETERS ASSESSED BY PERFUSION MR-IMAGING - PRELIMINARY-REPORT", Journal of the neurological sciences, 157(1), 1998, pp. 67-72

Abstract

Thalamic lesions may induce a diffuse hypometabolism and subsequent decrease of cortical cerebral blood how (rCBF) and cerebral blood volume (rCBV). Up to now PET was used to assess these changes. However thislatter method cannot be applied routinely to stroke patients because it is expensive and not currently available. The purpose of this preliminary study was to evaluate the effects of 'pure metabolic depression' induced by thalamic stroke on rCBV and rCBF by using a non invasive method perfusion-MRT. Two patients experienced aphasia, with motor andsensory impairment related to thalamic hemorrhage. Four weeks later, dynamic T2-weighted echo planar imaging was used to produce perfusion-MR images during an intravenous bolus injection of gadopentetate dimeglumine. A decrease of cortical rCBV and rCBF mainly confined to sensorimotor cortex was observed in both cases ipsilateral to the lesion. Although a sequential assessment of this abnormalities is needed in a larger series of patients in order to establish relevant correlations with neurological status, this preliminary study indicates that perfusion-MRI might be a practical and promising tool in the assessment of cortical rCBV and rCBF changes. (C) 1998 Elsevier Science B.V.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/11/20 alle ore 14:10:43