Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
CARDIOPULMONARY EXERCISE TESTING IN EVALUATION OF THE FUNCTIONAL-CAPACITY OF SURVIVORS OF CHILDHOOD-CANCER
Autore:
HOGARTY AN; SILBER JH; PARIDON SM;
Indirizzi:
CHILDRENS HOSP PHILADELPHIA,ABRAMSON BLDG,RM 702G,34TH ST & CIV CTR BLVD PHILADELPHIA PA 19104 UNIV PENN,SCH MED,DEPT PEDIAT,DIV CARDIOL PHILADELPHIA PA 19104
Titolo Testata:
Progress in pediatric cardiology
fascicolo: 3, volume: 8, anno: 1998,
pagine: 109 - 119
SICI:
1058-9813(1998)8:3<109:CETIEO>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
BONE-MARROW TRANSPLANTATION; ACUTE LYMPHOBLASTIC-LEUKEMIA; MEDIASTINAL RADIATION-THERAPY; DISEASE FOLLOWING TREATMENT; QT INTERVAL PROLONGATION; LONG-TERM SURVIVORS; DOXORUBICIN CARDIOTOXICITY; RADIONUCLIDE ANGIOGRAPHY; HODGKINS-DISEASE; CARDIAC-FUNCTION;
Keywords:
CARDIOPULMONARY EXERCISE TESTING; PEDIATRIC CANCER SURVIVORS; ANTHRACYCLINE CARDIOTOXICITY; MAXIMUM CARDIAC INDEX; OXYGEN CONSUMPTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
69
Recensione:
Indirizzi per estratti:
Citazione:
A.N. Hogarty et al., "CARDIOPULMONARY EXERCISE TESTING IN EVALUATION OF THE FUNCTIONAL-CAPACITY OF SURVIVORS OF CHILDHOOD-CANCER", Progress in pediatric cardiology, 8(3), 1998, pp. 109-119

Abstract

Progress in the treatment of pediatric cancer has resulted in a growing population of survivors of malignancy treated in childhood. These individuals may have evidence of multiple organ system impairment related to oncologic disease and its therapy. Metabolic exercise testing measures cardiovascular, pulmonary and musculoskeletal components of maximal exercise performance, quantifying functional capacity. This information has been used to describe the clinical syndromes related to anthracycline exposure, radiation therapy and bone marrow transplantation. Impaired performance at exercise testing has been quantified in general as decreased endurance, increased symptomatology and excess cardiac arrhythmias. Specific evaluation of the cardiovascular system in survivors of childhood cancer demonstrates impaired aerobic capacity and impaired hemodynamic response to exercise, with relatively increased heart rate, decreased stroke volume and decreased maximal cardiac index. These abnormalities correlate with risk factors for cardiovascular impairment: increased anthracycline dose, female sex, younger age at treatment and longer time to follow-up evaluation. Changes in musculoskeletal function impact variably on exercise capacity. Metabolic exercise testing which measures the integrated function of multiple organ systems identifies subclinical abnormalities useful in monitoring functional capacity and guiding intervention. (C) 1998 Elsevier Science Ireland Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 03:05:44