Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
PREVALENCE, RISK-FACTORS, AND ACCURACY OF CYTOLOGIC SCREENING FOR CERVICAL INTRAEPITHELIAL NEOPLASIA IN WOMEN WITH THE HUMAN-IMMUNODEFICIENCY-VIRUS
Autore:
MAIMAN M; FRUCHTER RG; SEDLIS A; FELDMAN J; CHEN P; BURK RD; MINKOFF H;
Indirizzi:
SUNY HLTH SCI CTR,DEPT OBSTET & GYNECOL,BOX 24,450 CLARKSON AVE BROOKLYN NY 11203 SUNY HLTH SCI CTR,DEPT PREVENT MED BROOKLYN NY 11203 SUNY HLTH SCI CTR,DEPT PATHOL BROOKLYN NY 11203 YESHIVA UNIV ALBERT EINSTEIN COLL MED,DEPT PEDIAT BRONX NY 10461
Titolo Testata:
Gynecologic oncology
fascicolo: 3, volume: 68, anno: 1998,
pagine: 233 - 239
SICI:
0090-8258(1998)68:3<233:PRAAOC>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
SEROPOSITIVE WOMEN; INFECTED WOMEN; PAPANICOLAOU SMEAR; ABNORMALITIES; LESIONS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
M. Maiman et al., "PREVALENCE, RISK-FACTORS, AND ACCURACY OF CYTOLOGIC SCREENING FOR CERVICAL INTRAEPITHELIAL NEOPLASIA IN WOMEN WITH THE HUMAN-IMMUNODEFICIENCY-VIRUS", Gynecologic oncology, 68(3), 1998, pp. 233-239

Abstract

Objectives. The objective was to evaluate the sensitivity and specificity of cervical cytology in women infected with the human immunodeficiency virus (HIV), risk factors for abnormal cytology in HIV-infected and uninfected women, and risk factors for histologic diagnosis of cervical intraepithelial neoplasia (CIN) in HIV-infected women. Methods. Methods included a cross-sectional analysis of cervical cytology, colposcopic impression, and histology in 248 HIV-infected women and multivariate analyses of risk factors for abnormal cytology in 253 HIV-infected and 220 uninfected women and risk factors for CIN in 186 HIV-infected women. Results. The sensitivity and specificity of cytology for all CIN grades were 0.60 and 0.80 and, for high-grade GIN, 0.83 and 0.74. The prevalence of abnormal cytology was 32.9% in HIV-infected and 7.6% in HIV-negative women. Independent risk factors for abnormal cytology were immunodeficiency [odds ratio (OR) 8-17, P < 0.001] and human papillomavirus (HPV) infection (OR = 5, P < 0.001). The prevalence of CIN on histology was 32% in HIV-infected women, and the only independent risk factor for CIN was oncogenic HPV type (OR = 5, P = 0.005). Conclusion. Given the high prevalence of abnormal cytology and CIN in HIV-infected women, cytologic screening has significant limitations. Both immunodeficiency and type of HPV infection are important risk factors. (C) 1998 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/21 alle ore 07:39:04