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Titolo:
BASE IMAGING - A NEW SPIN-LABELING TECHNIQUE FOR MEASURING ABSOLUTE PERFUSION CHANGES
Autore:
SCHWARZBAUER C; HEINKE W;
Indirizzi:
MAX PLANCK INST COGNIT NEUROSCI,INSELSTR 22-26 D-04103 LEIPZIG GERMANY MAX PLANCK INST NEUROPSYCHOL FORSCH D-04103 LEIPZIG GERMANY KLIN & POLKLIN ANASTHESIOL & INTENSIVTHERAPIE LEIPZIG GERMANY
Titolo Testata:
Magnetic resonance in medicine
fascicolo: 5, volume: 39, anno: 1998,
pagine: 717 - 722
SICI:
0740-3194(1998)39:5<717:BI-ANS>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBRAL BLOOD-FLOW; POSITRON EMISSION TOMOGRAPHY; FUNCTIONAL MRI; HUMAN-BRAIN; INTRAVENOUS (H2O)-O-15; ARTERIAL WATER; TRANSIT-TIME; INVERSION; SENSITIVITY; OXYGENATION;
Keywords:
CEREBRAL BLOOD FLOW; PERFUSION; FMRI;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
C. Schwarzbauer e W. Heinke, "BASE IMAGING - A NEW SPIN-LABELING TECHNIQUE FOR MEASURING ABSOLUTE PERFUSION CHANGES", Magnetic resonance in medicine, 39(5), 1998, pp. 717-722

Abstract

A new technique for magnetic resonance imaging of absolute perfusion changes that uses magnetically labeled tissue water proton spins as a freely diffusible tracer is described. It consists of unprepared basis(BA) images that serve as a reference and selective (SE) inversion prepared images that are sensitive to perfusion changes. In the present study, the BASE technique was applied to functional neuroimaging. BA and SE images were alternatingly and repeatedly acquired during periodsof visual stimulation and control, Visual stimulation was achieved with an alternating black/white checkerboard operating at a frequency of8 Hz. Maps of the absolute cerebral blood flow changes (Delta CBF) were calculated from the image intensities of the corresponding BA and SE images, The individual mean values of Delta CBF measured in five healthy volunteers ranged from 69 +/- 18 to 99 +/- 26 ml/min/100 g. Sincethe BASE technique does not require nonselective spin inversion, it can be used with small transmit/receive head coils (e.g., surface coils). In addition, the BASE technique is robust against a mismatch of theinversion and detection slice profiles.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/09/20 alle ore 00:55:55