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Titolo:
A FAMILY-BASED ANALYSIS OF THE ASSOCIATION OF THE DOPAMINE D2 RECEPTOR (DRD2) WITH ALCOHOLISM
Autore:
EDENBERG HJ; FOROUD T; KOLLER DL; GOATE A; RICE J; VANEERDEWEGH P; REICH T; CLONINGER CR; NURNBERGER JI; KOWALCZUK M; WU B; LI TK; CONNEALLY PM; TISCHFIELD JA; WU W; SHEARS S; CROWE R; HESSELBROCK V; SCHUCKIT M; PORJESZ B; BEGLEITER H;
Indirizzi:
INDIANA UNIV,SCH MED,DEPT BIOCHEM & MOL BIOL,635 BARNHILL DR,MED SCI418 INDIANAPOLIS IN 46202 WASHINGTON UNIV,SCH MED ST LOUIS MO 63130 UNIV IOWA,SCH MED IOWA CITY IA 52242 UNIV CONNECTICUT,SCH MED FARMINGTON CT 00000 UNIV CALIF SAN DIEGO,SCH MED LA JOLLA CA 92093 SUNY HLTH SCI CTR BROOKLYN NY 11203
Titolo Testata:
Alcoholism, clinical and experimental research
fascicolo: 2, volume: 22, anno: 1998,
pagine: 505 - 512
SICI:
0145-6008(1998)22:2<505:AFAOTA>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
TAQI A1 ALLELE; DSM-III-R; LINKAGE DISEQUILIBRIUM; D2-DOPAMINE RECEPTOR; GENE DRD2; NO ASSOCIATION; AL ALLELE; UNITED-STATES; SUBSTANCE USE; USE DISORDERS;
Keywords:
ALCOHOLISM; DOPAMINE D2 RECEPTOR; ASSOCIATION STUDY; FAMILY STUDY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
71
Recensione:
Indirizzi per estratti:
Citazione:
H.J. Edenberg et al., "A FAMILY-BASED ANALYSIS OF THE ASSOCIATION OF THE DOPAMINE D2 RECEPTOR (DRD2) WITH ALCOHOLISM", Alcoholism, clinical and experimental research, 22(2), 1998, pp. 505-512

Abstract

The possible association of the DRD2 locus, and in particular the Taql-A1 allele, with alcoholism remains controversial, in part because ofdifferences in allele frequencies among populations, To avoid problems associated with differences in allele frequencies in different populations, we tested whether the DRD2 locus is associated with alcohol dependence in a large family-based sample. Neither the transmission/disequilibrium test nor the Affected Family-Based Controls test provide any evidence of linkage or association between the DRD2 locus and alcohol dependence.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 12:52:11