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Titolo: BENZO[C]QUINOLIZINIUMS - A NEW FAMILY OF INHIBITORS FOR PROTEIN-KINASE CKII
Autore: METTEY Y; VIERFOND JM; BAUDRY M; COCHET C; SARROUILHE D;
- Indirizzi:
- FAC MED & PHARM,CHIM ORGAN LAB,BP 199,34 RUE JARDIN PLANTES F-86005 POITIERS FRANCE FAC MED & PHARM,CHIM ORGAN LAB F-86005 POITIERS FRANCE CENG,DBMS,INSERM U244,CEA F-38054 GRENOBLE FRANCE FAC MED & PHARM,BIOL CELLULAIRE LAB F-86005 POITIERS FRANCE
- Titolo Testata:
- Bioorganic & medicinal chemistry letters
fascicolo: 8,
volume: 7,
anno: 1997,
pagine: 961 - 964
- SICI:
- 0960-894X(1997)7:8<961:B-ANFO>2.0.ZU;2-9
- Fonte:
- ISI
- Lingua:
- ENG
- Soggetto:
- CASEIN KINASE;
- Tipo documento:
- Article
- Natura:
- Periodico
- Settore Disciplinare:
- Science Citation Index Expanded
- Science Citation Index Expanded
- Citazioni:
- 11
- Recensione:
- Indirizzi per estratti:
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- Citazione:
- Y. Mettey et al., "BENZO[C]QUINOLIZINIUMS - A NEW FAMILY OF INHIBITORS FOR PROTEIN-KINASE CKII", Bioorganic & medicinal chemistry letters, 7(8), 1997, pp. 961-964
Abstract
A series of bicyclic enols 3 and tricyclic benzo[c]quinoliziniums 4 and 5 were prepared. and evaluated as inhibitors of protein kinase CKII. Of the seventeen derivatives examined, 6-hydroxy-benzo[c]quinolizinium 5d was the most potent inhibitor and exhibited a good selectivity for CKII in the micromolar range. (C) 1997 Elsevier Science Ltd.
ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/01/21 alle ore 04:06:22