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Titolo:
BENZO[C]QUINOLIZINIUMS - A NEW FAMILY OF INHIBITORS FOR PROTEIN-KINASE CKII
Autore:
METTEY Y; VIERFOND JM; BAUDRY M; COCHET C; SARROUILHE D;
Indirizzi:
FAC MED & PHARM,CHIM ORGAN LAB,BP 199,34 RUE JARDIN PLANTES F-86005 POITIERS FRANCE FAC MED & PHARM,CHIM ORGAN LAB F-86005 POITIERS FRANCE CENG,DBMS,INSERM U244,CEA F-38054 GRENOBLE FRANCE FAC MED & PHARM,BIOL CELLULAIRE LAB F-86005 POITIERS FRANCE
Titolo Testata:
Bioorganic & medicinal chemistry letters
fascicolo: 8, volume: 7, anno: 1997,
pagine: 961 - 964
SICI:
0960-894X(1997)7:8<961:B-ANFO>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
CASEIN KINASE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
11
Recensione:
Indirizzi per estratti:
Citazione:
Y. Mettey et al., "BENZO[C]QUINOLIZINIUMS - A NEW FAMILY OF INHIBITORS FOR PROTEIN-KINASE CKII", Bioorganic & medicinal chemistry letters, 7(8), 1997, pp. 961-964

Abstract

A series of bicyclic enols 3 and tricyclic benzo[c]quinoliziniums 4 and 5 were prepared. and evaluated as inhibitors of protein kinase CKII. Of the seventeen derivatives examined, 6-hydroxy-benzo[c]quinolizinium 5d was the most potent inhibitor and exhibited a good selectivity for CKII in the micromolar range. (C) 1997 Elsevier Science Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/01/21 alle ore 04:06:22