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Titolo:
APOPTOSIS REGULATING GENES IN PROSTATE-CANCER (REVIEW)
Autore:
JOHNSON MI; HAMDY FC;
Indirizzi:
UNIV NEWCASTLE UPON TYNE,SCH MED,DEPT SURG,SCH SURG SCI NEWCASTLE TYNE NE2 4HH TYNE & WEAR ENGLAND UNIV NEWCASTLE UPON TYNE,SCH MED,DEPT SURG,SCH SURG SCI NEWCASTLE TYNE NE2 4HH TYNE & WEAR ENGLAND
Titolo Testata:
Oncology Reports
fascicolo: 3, volume: 5, anno: 1998,
pagine: 553 - 557
SICI:
1021-335X(1998)5:3<553:ARGIP(>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
P53 PROTEIN ACCUMULATION; PROGRAMMED CELL-DEATH; TUMOR-SUPPRESSOR GENE; INTRAEPITHELIAL NEOPLASIA; IN-VIVO; PROGNOSTIC BIOMARKERS; ANDROGEN ABLATION; BAX GENE; BCL-2; EXPRESSION;
Keywords:
APOPTOSIS; PROSTATE CANCER;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
71
Recensione:
Indirizzi per estratti:
Citazione:
M.I. Johnson e F.C. Hamdy, "APOPTOSIS REGULATING GENES IN PROSTATE-CANCER (REVIEW)", Oncology Reports, 5(3), 1998, pp. 553-557

Abstract

Prostatic adenocarcinoma is emerging as a major cause of morbidity and mortality in the male population in the western world. Programmed cell death (apoptosis) in the prostate is activated by hormone ablation and is under the control of several regulating genes including the tumour suppressor gene p53 and the proto-oncogene bcl-2. Bcl-2 belongs toa rapidly expanding family of genes which form two functionally antagonistic groups controlling cell death and survival. Apoptosis regulating genes appear to play an important role in the development and progression of prostatic adenocarcinoma and offer a potential target for future therapeutic strategies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/21 alle ore 16:27:26