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Titolo:
TREATMENT OF BENIGN HEPATIC CYSTS BY INSTILLATION OF TETRACYCLINE HYDROCHLORIDE
Autore:
LOPES HMNR; PORTELA FAS; PONTES JMS; LEITAO MJC; RIBEIRO JCBMD; FREITAS DD;
Indirizzi:
COIMBRA UNIV HOSP,DEPT GASTROENTEROL,PRACETA PROF MOTA PINTO P-3049 COIMBRA PORTUGAL
Titolo Testata:
Hepato-gastroenterology
fascicolo: 20, volume: 45, anno: 1998,
pagine: 496 - 499
SICI:
0172-6390(1998)45:20<496:TOBHCB>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERCUTANEOUS ASPIRATION; LAPAROSCOPIC MANAGEMENT; ALCOHOL SCLEROTHERAPY; SURGICAL-MANAGEMENT; NONPARASITIC CYSTS; LIVER CYST; SCLEROSIS; DISEASE; DIAGNOSIS; INJECTION;
Keywords:
BENIGN HEPATIC CYSTS; TREATMENT; TETRACYCLINE HYDROCHLORIDE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
H.M.N.R. Lopes et al., "TREATMENT OF BENIGN HEPATIC CYSTS BY INSTILLATION OF TETRACYCLINE HYDROCHLORIDE", Hepato-gastroenterology, 45(20), 1998, pp. 496-499

Abstract

BACKGROUND/AIMS: Despite the high frequency of benign hepatic cysts, they rarely cause symptoms. Large cysts, however, may produce clinicalmanifestations. In these cases, ultrasonography-guided therapy has been proposed. We report the results of this therapy in patients with symptomatic benign hepatic cysts. METHODOLOGY: Seven patients with non-parasitic, non-neoplastic benign hepatic cysts were submitted to fine-needle ultrasonography-guided aspiration, followed by injection of diluted tetracycline hydrochloride (1 g). In all cases, cytology, tumour markers and microbiology analysis of aspirates were performed. One patient required two sessions. The grade of patient satisfaction and ultrasonography changes were assessed 1, 3 and 6 months after the procedure. RESULTS: Cyst size decreased in all patient, with total collapse in three. No major complications occured. Cytology, alpha fetoprotein, CA19.9, CEA and microbiology of the cyst fluid confirmed the initial ultrasonographic diagnosis of simple biliary cysts. Clinical complaints improved in 2 cases, and 5 patients became assymptomatic. Ultrasonography evaluation 3 months after the procedure was more reliable in predicting successful treatment. CONCLUSION: Intracystic instillation of tetracycline hydrochloride is an effective and safe technique and may become the first choice therapy for benign hepatic cysts.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/10/20 alle ore 02:40:45