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Titolo:
THE EFFECT OF DIETARY-SODIUM INTAKE ON BIOCHEMICAL MARKERS OF BONE METABOLISM IN YOUNG-WOMEN
Autore:
GINTY F; FLYNN A; CASHMAN KD;
Indirizzi:
NATL UNIV IRELAND UNIV COLL CORK,DEPT NUTR CORK IRELAND NATL UNIV IRELAND UNIV COLL CORK,DEPT NUTR CORK IRELAND
Titolo Testata:
British Journal of Nutrition
fascicolo: 4, volume: 79, anno: 1998,
pagine: 343 - 350
SICI:
0007-1145(1998)79:4<343:TEODIO>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
URINARY CALCIUM EXCRETION; POSTMENOPAUSAL WOMEN; HYDROXYPROLINE EXCRETION; SALT; ABSORPTION; RESORPTION; POPULATION; POTASSIUM; CAFFEINE; DENSITY;
Keywords:
SODIUM; BONE; BIOCHEMICAL MARKERS; PREMENOPAUSAL WOMEN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
35
Recensione:
Indirizzi per estratti:
Citazione:
F. Ginty et al., "THE EFFECT OF DIETARY-SODIUM INTAKE ON BIOCHEMICAL MARKERS OF BONE METABOLISM IN YOUNG-WOMEN", British Journal of Nutrition, 79(4), 1998, pp. 343-350

Abstract

To investigate the effect of a low (80 mmol/d) or high (180 mmol/d) Na intake for 14d on biochemical markers of bone turnover in Na-sensitive and Na-non-sensitive healthy young women, twenty-nine subjects werescreened for responsiveness of urinary Ca excretion to increasing dietary Na intake (40, 80, 120 and 200 mmol/d for 7d). Ina crossover study, the eight Na-sensitive and eight of the twenty-one Na-non-sensitivesubjects were randomly assigned to diets containing either 80 or 180 mmol Na/d for 14 d followed by crossover to the alternative diet for afurther 14 d. Dietary Ca was restricted to 12.5 mmol/d throughout. During each dietary period, fasting morning first void urine samples (last 3 d) and fasting blood serum samples (morning of twelfth day) were collected. Increasing Na intake from 80 to 180 mmol/d increased urinary Na about twofold in both the Na-sensitive and Na-non-sensitive groups and increased urinary Ca excretion (by 73 %) in the Na-sensitive group only. Biochemical markers of bone resorption (urinary pyridinoline and deoxypyridinoline) and bone formation (serum osteocalcin and bone-specific alkaline phosphatase; EC 3.1.3.1) were unaffected by increasing dietary Na in either group. It is concluded that the Na-induced calciuria observed in the Na-sensitive healthy young women did not resultin increased bone resorption or turnover and, despite restricted Ca intake, adaptation of dietary Ca absorption may have compensated for the increased urinary Ca loss.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 15:52:40