Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
PROTON MR SPECTROSCOPY IN LESCH-NYHAN-DISEASE
Autore:
DAVANZO P; KE Y; THOMAS MA; ANDERSON C; KING B; BELIN T; LEVITT J; CURRAN J; GUZE B;
Indirizzi:
UNIV CALIF LOS ANGELES,INST NEUROPSYCHIAT,DEPT PSYCHIAT,ROOM 48-243C LOS ANGELES CA 90024 UNIV CALIF LOS ANGELES,DEPT PSYCHIAT & BEHAV SCI LOS ANGELES CA 90024 UNIV CALIF LOS ANGELES,DEPT RADIOL SCI LOS ANGELES CA 90024 UNIV CALIF LOS ANGELES,DEPT ANESTHESIOL LOS ANGELES CA 90024 UNIV CALIF LOS ANGELES,DEPT BIOSTAT LOS ANGELES CA 90024
Titolo Testata:
American journal of neuroradiology
fascicolo: 4, volume: 19, anno: 1998,
pagine: 672 - 674
SICI:
0195-6108(1998)19:4<672:PMSIL>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
MULTIPLE-SCLEROSIS LESIONS; APPEARING WHITE-MATTER; HUMAN-BRAIN INVIVO; H-1-NMR SPECTROSCOPY; DOPAMINE DEFICIENCY; NMR-SPECTROSCOPY; IN-VIVO; BEHAVIOR; RATS; GLUTAMINE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
P. Davanzo et al., "PROTON MR SPECTROSCOPY IN LESCH-NYHAN-DISEASE", American journal of neuroradiology, 19(4), 1998, pp. 672-674

Abstract

In vivo proton spectra for Pour patients with Lesch-Nyhan disease andfour control subjects matched for age and sex were acquired from voxels (1.5 x 1.5 x 1.5 cm(3)) placed in the prefrontal cortex and striatum. The patients with Lesch-Nyhan disease had decreased metabolites, especially N-acetylaspartate and glutamate/glutamine, only in the prefrontal cortex as compared with the control group. These findings suggestaxonal loss in the prefrontal area of this population. The cortical glutamate/glutamine peak decrement does not confirm cytopathologic studies of Lesch-Nyhan disease and deserves further investigation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 13:39:05