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Titolo:
RHODOCOCCUS-EQUI PNEUMONIA IN PATIENTS INFECTED WITH THE HUMAN-IMMUNODEFICIENCY-VIRUS - REPORT OF 2 CASES AND REVIEW OF THE LITERATURE
Autore:
CAPDEVILA JA; BUJAN S; GAVALDA J; FERRER A; PAHISSA A;
Indirizzi:
HOSP GEN VALLE HEBRON,SERV MALALTIES INFECCIOSES,PASSEIG VALL HEBRON 119 E-08035 BARCELONA SPAIN HOSP GEN VALLE HEBRON,MICROBIOL SERV BARCELONA SPAIN
Titolo Testata:
Scandinavian journal of infectious diseases
fascicolo: 6, volume: 29, anno: 1997,
pagine: 535 - 541
SICI:
0036-5548(1997)29:6<535:RPIPIW>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
IMMUNE-DEFICIENCY-SYNDROME; HIV-POSITIVE PATIENT; CORYNEBACTERIUM-EQUI; PULMONARY MALACOPLAKIA; OPPORTUNISTIC PATHOGEN; LUNG ABSCESS; ANTIMICROBIAL SUSCEPTIBILITY; CAVITARY PNEUMONIA; SYNDROME AIDS; FOALS;
Tipo documento:
Article
Natura:
Periodico
Citazioni:
71
Recensione:
Indirizzi per estratti:
Citazione:
J.A. Capdevila et al., "RHODOCOCCUS-EQUI PNEUMONIA IN PATIENTS INFECTED WITH THE HUMAN-IMMUNODEFICIENCY-VIRUS - REPORT OF 2 CASES AND REVIEW OF THE LITERATURE", Scandinavian journal of infectious diseases, 29(6), 1997, pp. 535-541

Abstract

Rhodococcus equi is a cause of lung infection in immunosuppressed hosts. Since the start of the HIV epidemic, 76 cases of R. equi lung infection (MEDLINE 1985-96) affecting this population have been described. We report 2 additional cases and review the clinical data, radiological findings, treatment and outcome of these 78 patients. The mean age of these patients was 33 y; 69 were male. 71 met the criteria for AIDS(CDC 1993). Fever and cough were the presenting complaints in the majority of patients (84.3%). A single cavitary lung lesion in the upper robes was the most common radiological finding (57.7%), although multiple cavitations, alveolar infiltrates and pleural effusion were also found, Treatment usually was based on synergistic antibiotic combinations for a long period of time determined on an individual basis. Surgery was performed only in 11 patients. Death attributable directly to R.equi infection is low (15.4%), however only half of the patients (53.8%) were completely cured. We conclude that R. equi infection should be strongly considered in any HIV patient who presents with cavitary lesions in the lung, especially if mycobacteria are not identified. Treatment must be based on synergistic antibiotic combinations, and surgery relegated to cases of chronic single cavitary lesions not respondingto antibiotics.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/07/20 alle ore 16:51:43