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Titolo:
FERTILITY RESULTS AFTER OVARIAN TRANSPOSITION FOR PELVIC MALIGNANCIESTREATED BY EXTERNAL IRRADIATION OR BRACHYTHERAPY
Autore:
MORICE P; THIAMBA R; CASTAIGNE D; HAIEMEDER C; GERBAULET A; PAUTIER P; DUVILLARD P; MICHEL G;
Indirizzi:
INST GUSTAVE ROUSSY,SERV CHIRURG GYNECOL,39 RUE CAMILLE DESMOULINS F-94805 VILLEJUIF FRANCE
Titolo Testata:
Human reproduction
fascicolo: 3, volume: 13, anno: 1998,
pagine: 660 - 663
SICI:
0268-1161(1998)13:3<660:FRAOTF>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
CERVICAL-CANCER; RADICAL HYSTERECTOMY; RADIATION-THERAPY; HODGKINS-DISEASE; RADIOTHERAPY; PRESERVATION; OOPHOROPEXY; EXPERIENCE;
Keywords:
FERTILITY; OVARIAN TRANSPOSITION; PELVIC CANCER;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
P. Morice et al., "FERTILITY RESULTS AFTER OVARIAN TRANSPOSITION FOR PELVIC MALIGNANCIESTREATED BY EXTERNAL IRRADIATION OR BRACHYTHERAPY", Human reproduction, 13(3), 1998, pp. 660-663

Abstract

The aim of this study was to assess the fertility outcome after ovarian transposition with uterine conservation and pelvic irradiation therapy for pelvic cancer. A total of 37 consecutive cases were reviewed, Of these, 27 patients were treated for a clear cell adenocarcinoma of the vagina and/or the cervix (group 1), nine for an ovarian pure dysgerminoma and one for a para-uterine soft tissue sarcoma (group 2), The pregnancy rate was 15% (4/27) in group 1 and 80% (8/10) in group 2 (P = 0.01). A total of 18 pregnancies was observed in 12 patients, Of these, 16 pregnancies were obtained spontaneously and two after in-vitro fertilization. Of the spontaneous pregnancies, 12 (75%) were observed with ovaries still in the abdominal cavity (not repositioned), These results show that the prognosis for fertility is excellent after ovarian transposition and irradiation in patients with morphologically normal genital tracts (group 2), The prognosis is not as good for patients treated for a clear cell adenocarcinoma of the vagina and/or the cervix who may have morphological and/or functional anomalies of the genital tract, following exposure to diethylstilboestrol and brachytherapy (group 1), Furthermore, these results show that repositioning of the ovary is not essential to achieve pregnancy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 18:24:01