Catalogo Articoli (Spogli Riviste)

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Titolo:
NEW APPROACHES TO SUPPORTING THE FAILING LIVER
Autore:
CAO S; ESQUIVEL CO; KEEFFE EB;
Indirizzi:
STANFORD UNIV,MED CTR,SCH MED,DEPT SURG STANFORD CA 94305 STANFORD UNIV,MED CTR,SCH MED,DEPT MED STANFORD CA 94305
Titolo Testata:
Annual review of medicine
, volume: 49, anno: 1998,
pagine: 85 - 94
SICI:
0066-4219(1998)49:<85:NATSTF>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
FULMINANT HEPATIC-FAILURE; HYBRID BIOARTIFICIAL LIVER; HEPATOCYTE ISOLATION; PARTIAL-HEPATECTOMY; ASSIST DEVICE; PIG LIVERS; REGENERATION; SYSTEMS; RATS; HEMOPERFUSION;
Keywords:
LIVER TRANSPLANTATION; FULMINANT HEPATIC FAILURE; ARTIFICIAL LIVER;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
44
Recensione:
Indirizzi per estratti:
Citazione:
S. Cao et al., "NEW APPROACHES TO SUPPORTING THE FAILING LIVER", Annual review of medicine, 49, 1998, pp. 85-94

Abstract

With the continued, growing disparity between the numbers of organ donations and patients waiting for liver transplantation, various efforts have been made to optimize the allocation of organs, as well as to devise means to support the failing liver. Over the years, the development of bioartificial liver-assist devices has aimed at replacing the three main functions of hepatocytes, which are synthetic, metabolic, and excretory. The application of porcine hepatocytes in humans to carryout biotransformation, as well as other metabolic functions and refinement of the membrane separator, have yielded some promising results in supporting patients with acute liver failure. Further advances will need to be made before these bioartificial devices can be considered for routine application in clinical settings.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 12:39:21