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Titolo:
AN APPROACH TO USE AN UNUSUAL ADENOSINE TRANSPORTER TO SELECTIVELY DELIVER POLYAMINE ANALOGS TO TRYPANOSOMES
Autore:
TYE CK; KASINATHAN G; BARRETT MP; BRUN R; DOYLE VE; FAIRLAMB AH; WEAVER R; GILBERT IH;
Indirizzi:
UNIV WALES COLL CARDIFF,WELSH SCH PHARM,REDWOOD BLDG,KING EDWARD VII AVE CARDIFF CF1 3XF S GLAM WALES UNIV WALES COLL CARDIFF,WELSH SCH PHARM CARDIFF CF1 3XF S GLAM WALES UNIV GLASGOW,INST BIOMED & LIFE SCI,DIV INFECT & IMMUN GLASGOW G12 8QQ LANARK SCOTLAND UNIV DUNDEE,DEPT BIOCHEM DUNDEE DD1 4HN SCOTLAND SWISS TROP INST CH-4002 BASEL SWITZERLAND
Titolo Testata:
Bioorganic & medicinal chemistry letters
fascicolo: 7, volume: 8, anno: 1998,
pagine: 811 - 816
SICI:
0960-894X(1998)8:7<811:AATUAU>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANTITUMOR; BRUCEI;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
C.K. Tye et al., "AN APPROACH TO USE AN UNUSUAL ADENOSINE TRANSPORTER TO SELECTIVELY DELIVER POLYAMINE ANALOGS TO TRYPANOSOMES", Bioorganic & medicinal chemistry letters, 8(7), 1998, pp. 811-816

Abstract

In this paper we describe an approach to selectively deliver compounds to trypanosomes using an adenosine transporter which is unique to the trypanosome. Various polyamine analogues have been attached to knownsubstrates of this adenosine transporter. The compounds prepared interact specifically with the adenosine transporter, some with a similar efficiency to berenil, a known substrate. (C) 1998 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/21 alle ore 10:11:12