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Titolo:
DECREASED SERUM CHOLINE CONCENTRATIONS IN HUMANS AFTER SURGERY, CHILDBIRTH, AND TRAUMATIC HEAD-INJURY
Autore:
ULUS IH; OZYURT G; KORFALI E;
Indirizzi:
ULUDAG UNIV,FAC MED,DEPT PHARMACOL & CLIN PHARMACOL TR-16059 BURSA TURKEY ULUDAG UNIV,FAC MED,DEPT ANAESTHESIOL & REANIMAT TR-16059 BURSA TURKEY ULUDAG UNIV,FAC MED,DEPT NEUROSURG TR-16059 BURSA TURKEY
Titolo Testata:
Neurochemical research
fascicolo: 5, volume: 23, anno: 1998,
pagine: 727 - 732
SICI:
0364-3190(1998)23:5<727:DSCCIH>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
RAT CORPUS STRIATUM; TYROSINE-HYDROXYLASE; ACETYLCHOLINE-RELEASE; CONSCIOUS RATS; BETA-ENDORPHIN; BRAIN; STIMULATION; METABOLITES; DEFICIENCY; INDUCTION;
Keywords:
CHOLINE; SERUM CHOLINE; SURGICAL STRESS; PREGNANCY; CHILDBIRTH STRESS; TRAUMATIC INJURY; HEAD TRAUMA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
46
Recensione:
Indirizzi per estratti:
Citazione:
I.H. Ulus et al., "DECREASED SERUM CHOLINE CONCENTRATIONS IN HUMANS AFTER SURGERY, CHILDBIRTH, AND TRAUMATIC HEAD-INJURY", Neurochemical research, 23(5), 1998, pp. 727-732

Abstract

The serum levels of choline decreased by approximately 50% in patients having a surgery under general as well as epidural anesthesia. The decrease is lasts for two days after surgery. Intravenous administration of succinylcholine, either by a single bolus injection or by a slow continuous infusion, increased the serum choline levels several folds during surgery. In these patients, a significant decrease in the serumcholine levels was observed one and two days after surgery. In 16 pregnant women at the term, serum choline levels were higher than the value observed in 19 nonpregnant women. The serum choline levels decreased by about 40% or 60% after having a childbirth either by vaginal delivery or caesarean section, respectively. Serum choline levels in bloodobtained from 9 patients with traumatic head injury were significantly lower than the observed levels in blood samples obtained from healthy volunteers. These observations show that serum choline levels increase during pregnancy and decrease during stressful situations in humans.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 06:36:32