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Titolo:
OCULAR MANIFESTATIONS OF GIANT-CELL ARTERITIS
Autore:
HAYREH SS; PODHAJSKY PA; ZIMMERMAN B;
Indirizzi:
UNIV IOWA HOSP & CLIN,DEPT OPHTHALMOL & VISUAL SCI,COLL MED,200 HAWKINS DR IOWA CITY IA 52242 UNIV IOWA HOSP & CLIN,DEPT PREVENT MED & ENVIRONM HLTH,COLL MED IOWA CITY IA 52242
Titolo Testata:
American journal of ophthalmology
fascicolo: 4, volume: 125, anno: 1998,
pagine: 509 - 520
SICI:
0002-9394(1998)125:4<509:OMOGA>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
ISCHEMIC OPTIC NEUROPATHY; TEMPORAL ARTERITIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
S.S. Hayreh et al., "OCULAR MANIFESTATIONS OF GIANT-CELL ARTERITIS", American journal of ophthalmology, 125(4), 1998, pp. 509-520

Abstract

PURPOSE: To report the ocular manifestations of giant cell arteritis using the strict criterion of a positive temporal artery biopsy for diagnosis of giant cell arteritis, METHODS: In a prospective study from 1973 to 1995, we investigated 170 patients whose diagnosis of giant cell arteritis was confirmed on temporal artery biopsy, At the initial visit, all patients were questioned regarding systemic and ocular signsand symptoms of giant cell arteritis and underwent ophthalmic, erythrocyte sedimentation rate (Westergren), and C-reactive protein evaluations, Any patient with a high index of suspicion of giant cell arteritis was immediately started on systemic corticosteroid therapy and had temporal artery biopsy performed as soon as possible, RESULTS: Eighty-five (50.0%) of the 170 patients with giant cell arteritis proven by temporal artery biopsy presented with ocular involvement, Ocular symptoms in patients with ocular involvement were visual loss of varying severity in 83 (97.7%), amaurosis fugax in 26 (30.6%), diplopia in five (5.9%), and eye pain in seven (8.2%); ocular ischemic lesions consisted of arteritic anterior ischemic optic neuropathy in 69 (81.2%), centralretinal artery occlusion in 12 (14.1%), cilioretinal artery occlusionin 12 (of 55 patients with satisfactory fluorescein angiography [21.8%]), posterior ischemic optic neuropathy in six (7.1%), and ocular ischemia in one (1.2%), In almost every patient with giant cell arteritis, fluorescein fundus angiography disclosed occlusive disease of the posterior ciliary arteries, CONCLUSION: Because giant cell arteritis is a potentially blinding disease and its early diagnosis is the key to preventing blindness, it is important to recognize its various ocular manifestations. (C) 1998 by Elsevier Science Inc. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/09/20 alle ore 05:03:50