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Titolo:
DIALYSIS HYPERSENSITIVITY - A FADING PROBLEM
Autore:
DEFILIPPI C; PIAZZA V; EFFICACE E; GALLI F; PISATI P; APRILE C; SALVADEO A;
Indirizzi:
IRCCS,MED CTR PAVIA,DIV NEPRHOL & DIALYSIS,CLIN DEL LAVORO & RIABILITAZ,FDN SALVATORE MAUGERI I-27100 PAVIA ITALY
Titolo Testata:
Blood purification
fascicolo: 2, volume: 16, anno: 1998,
pagine: 66 - 71
SICI:
0253-5068(1998)16:2<66:DH-AFP>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
ETHYLENE-OXIDE; ANAPHYLACTOID REACTIONS; IGE; DYSREGULATION; HEMODIALYSIS; ANTIBODIES; PRURITUS; ALLERGY; UREMIA;
Keywords:
DIALYSIS; UREMIA; HYPERSENSITIVITY; IGE; ALLERGENS; ETHYLENE OXIDE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
C. Defilippi et al., "DIALYSIS HYPERSENSITIVITY - A FADING PROBLEM", Blood purification, 16(2), 1998, pp. 66-71

Abstract

Allergic-type reactions experienced by patients on chronic hemodialysis are frequently reported in the literature, often related to compounds released during the hemodialysis sessions, in particular ethylene oxide (ETO). In these studies, dialysis patients seem to have higher values of ISE than those observed in a reference population. The aim of our work was to investigate IgE-related parameters of 126 dialysis patients in comparison with two control groups composed of healthy subjects and predialysis patients, ISE values were not significantly different in nonallergic dialysis patients, with a geometric mean (X) of 27.5kU/l, when compared to healthy controls (X = 38 kU/l) and predialysissubjects (X = 40.7 kU/l). Higher values of IgE (X = 74.1 kU/l) were detected in allergic dialysis patients. However, only 3 patients, all without detectable antibodies against ETO, complained of anaphylactic symptoms during dialysis sessions in a 4-year surveillance period, At variance, 6 symptom-free patients carried IgE antibodies against ETO (range 0.7-15 kU/l), usually with high total IgE, Our results suggest a reduced frequency of hypersensitivity reactions during dialysis sessions. Furthermore, uremia does not alter IgE reactivity in the predialysis period or after longterm maintenance dialysis treatment.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/21 alle ore 09:27:09