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Titolo:
GENETIC INFLUENCES IN ANTISOCIAL PERSONALITY AND DRUG-USE DISORDERS
Autore:
VANDENBREE MBM; SVIKIS DS; PICKENS RW;
Indirizzi:
NIDA,INTRAMURAL RES PROGRAM,5500 NATHAN SHOCK DR BALTIMORE MD 21224 JOHNS HOPKINS UNIV,SCH MED,DEPT PSYCHIAT & BEHAV SCI BALTIMORE MD 21224
Titolo Testata:
Drug and alcohol dependence
fascicolo: 3, volume: 49, anno: 1998,
pagine: 177 - 187
SICI:
0376-8716(1998)49:3<177:GIIAPA>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
CROSS-FOSTERING ANALYSIS; SUBSTANCE-ABUSE; ENVIRONMENTAL-FACTORS; PSYCHIATRIC-DISORDERS; SEX-DIFFERENCES; ALCOHOL-ABUSE; TWIN PAIRS; FAMILIAL TRANSMISSION; PETTY CRIMINALITY; SWEDISH ADOPTEES;
Keywords:
ANTISOCIAL PERSONALITY DISORDER; SUBSTANCE USE DISORDER; COMORBIDITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
95
Recensione:
Indirizzi per estratti:
Citazione:
M.B.M. Vandenbree et al., "GENETIC INFLUENCES IN ANTISOCIAL PERSONALITY AND DRUG-USE DISORDERS", Drug and alcohol dependence, 49(3), 1998, pp. 177-187

Abstract

While an association between antisocial personality disorder (APD) and substance use disorder (SUD) has been frequently observed, the causes of the comorbidity remain unclear. Adoption and twin studies have found evidence of both genetic and environmental influences in APD and SUD. Therefore, comorbidity between APD and SUD may be the result of shared genetic influences, shared environmental influences, or a combination of the two. However. only a limited number of adoption and twin studies have addressed this issue and the results have not been conclusive. In future studies. a distinction should be made between alcohol and drug abuse and between juvenile and adult APD symptoms. Twin samples of adequate size would allow use of structural equation analytical methods for estimation of the relative magnitude of genetic and environmental influences shared between the two conditions, as well as influences contributing to each specifically. Results would be highly relevant for the clinical setting as well as for efforts to identify the genes involved in either trait. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 06:57:54