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Titolo:
CEREBRAL-CORTEX DOES NOT MODULATE REGULATED DECREASE IN CORE TEMPERATURE DURING HYPOXEMIA IN RATS
Autore:
ROLLINS ELM; FEWELL JE;
Indirizzi:
UNIV CALGARY,HLTH SCI CTR,DEPT PHYSIOL & BIOPHYS,HERITAGE MED RES BLDG 206,3330 HOSP DR NW CALGARY AB T2N 4N1 CANADA UNIV CALGARY,HLTH SCI CTR,DEPT PHYSIOL & BIOPHYS CALGARY AB T2N 4N1 CANADA
Titolo Testata:
American journal of physiology. Regulatory, integrative and comparative physiology
fascicolo: 4, volume: 43, anno: 1998,
pagine: 1158 - 1161
SICI:
0363-6119(1998)43:4<1158:CDNMRD>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORTICAL SPREADING DEPRESSION; BEHAVIORAL THERMOREGULATION; THERMOSENSITIVE NEURONS; METABOLIC RESPONSES; CEREBROSPINAL-FLUID; BODY-TEMPERATURE; DENERVATED RATS; HYPOXIA; VASOPRESSIN; FEVER;
Keywords:
CORTICAL SPREADING DEPRESSION; FUNCTIONAL DECORTICATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
44
Recensione:
Indirizzi per estratti:
Citazione:
E.L.M. Rollins e J.E. Fewell, "CEREBRAL-CORTEX DOES NOT MODULATE REGULATED DECREASE IN CORE TEMPERATURE DURING HYPOXEMIA IN RATS", American journal of physiology. Regulatory, integrative and comparative physiology, 43(4), 1998, pp. 1158-1161

Abstract

In newborns and adults of a number of species including humans, exposure to acute hypoxemia produces a ''regulated'' decease in core temperature, the mechanism of which is unknown. Considering that various cortical areas participate in autonomic regulation including thermoregulation, the present experiments were carried out to test the hypothesis that the cerebral cortex plays a role in modulating the regulated decrease in core temperature during acute hyperemia. This hypothesis was tested by determining the core temperature response to acute hypoxemia in chronically instrumented adult Sprague-Dawley rats before and aftercortical spreading depression (i.e., functional decortication) was produced by the local application of potassium chloride to the dura overlying the cerebral hemispheres. There was no effect of cortical spreading depression on baseline core temperature. Core temperature decreased during acute hyperemia in a similar fashion when the cerebral cortexwas intact as well as during functional decortication. Thus our data do not support the hypothesis that the cerebral cortex modulates the regulated decrease in core temperature that occurs in adult rats duringacute hypoxemia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/09/20 alle ore 14:23:32