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Titolo:
THE PROJECTION FROM HIPPOCAMPAL AREA CA1 TO THE SUBICULUM SUSTAINS LONG-TERM POTENTIATION
Autore:
COMMINS S; GIGG J; ANDERSON M; OMARA SM;
Indirizzi:
UNIV DUBLIN TRINITY COLL,DEPT PSYCHOL DUBLIN 2 IRELAND UNIV DUBLIN TRINITY COLL,DEPT PSYCHOL DUBLIN 2 IRELAND
Titolo Testata:
NeuroReport
fascicolo: 5, volume: 9, anno: 1998,
pagine: 847 - 850
SICI:
0959-4965(1998)9:5<847:TPFHAC>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
FREELY MOVING RATS; SYNAPTIC TRANSMISSION; IN-VIVO; POSTSUBICULUM; SLICES; DEPOTENTIATION; ORGANIZATION; STIMULATION; INDUCTION; SYNTHASE;
Keywords:
CA1; HIPPOCAMPAL FORMATION; LONG-TERM POTENTIATION; SUBICULUM; SYNAPTIC PLASTICITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
S. Commins et al., "THE PROJECTION FROM HIPPOCAMPAL AREA CA1 TO THE SUBICULUM SUSTAINS LONG-TERM POTENTIATION", NeuroReport, 9(5), 1998, pp. 847-850

Abstract

LONG-TERM potentiation (LTP) is a popular model of the synaptic plasticity which may be engaged by the biological processes underlying learning and memory. Most available studies of LTP have concentrated on the analysis of LTP occurring in 'early' components of the hippocampal circuit (for example, dentate gyrus and area CA1). We examine here, forthe first time, LTP as it occurs in the massive, unidirectional projection from CA1 to the subiculum in vivo. We show that this projection sustains high-frequency stimulus-induced LTP (10 trains of 20 stimuli at 200 Hz; intertrain interval 2 s; LTP 181 +/- 9% at 30 min post-LTP induction). In addition, input-output (I/O) curves show a leftward shift for all stimulation values. (C) 1998 Rapid Science Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 18:54:09