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Titolo:
CENTRALIZED ONLINE HEMODIAFILTRATION SYSTEM UTILIZING PURIFIED DIALYSATE AS SUBSTITUTION FLUID
Autore:
SATO T; KOGA N;
Indirizzi:
KOGA HOSP,KIDNEY CTR,106-1 TENJIN CHO KURUME FUKUOKA 830 JAPAN
Titolo Testata:
Artificial organs
fascicolo: 4, volume: 22, anno: 1998,
pagine: 285 - 290
SICI:
0160-564X(1998)22:4<285:COHSUP>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Keywords:
CENTRALIZED ONLINE HEMODIAFILTRATION; ENDOTOXIN REMOVAL FILTER; DIALYSATE ENDOTOXIN LEVEL; LOW MOLECULAR WEIGHT PROTEIN REMOVAL; JOINT PAIN DECREASE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
7
Recensione:
Indirizzi per estratti:
Citazione:
T. Sato e N. Koga, "CENTRALIZED ONLINE HEMODIAFILTRATION SYSTEM UTILIZING PURIFIED DIALYSATE AS SUBSTITUTION FLUID", Artificial organs, 22(4), 1998, pp. 285-290

Abstract

We followed the guidelines of the Kyushu Society for Hemodiafiltration (HDF) Therapy on the purification of dialysate used as substitution fluid and clinically applied HDF using only 20 L or 15 L of substitution fluid in the pre-or postdilution mode, respectively. We used a centralized on-line HDF system consisting of a novel multi-patient dialysate delivery system applying 3 endotoxin (ET) removal filters in series, maintaining the LT level within the criteria limit below 1.0 IU/L (measured at the first filter outlet to be 0.1 IU/L and after the third filter to be below the sensitivity limit) irrespective of the fluctuation in the ET level of the tap water. Low molecular weight proteins (beta(2)-microglobulin, prolactin, alpha(1)-microglobulin, and alpha 1-acid glycoprotein) were more effectively removed in this HDF system than in conventional hemodialysis (HD) using the same dialyzer as that inthe HDF system, and the removal of these proteins in the HDF system was enhanced as their molecular weights increased. The clinical effect of the HDF system was demonstrated by a decrease in joint pain accompanied by improvement in joint motion in 6 dialysis patients followed over the longterm (100 weeks).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 20:54:32