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Titolo:
EFFECTS OF ALPHA-TOCOPHEROL NICOTINATE ON HEMORHEOLOGY AND RETINAL CAPILLARY BLOOD-FLOW IN FEMALE NIDDM WITH RETINOPATHY
Autore:
CHUNG TW; CHEN TZ; YU JJH; LIN SY; CHEN SC;
Indirizzi:
CHUNG YUAN CHRISTIAN UNIV,DEPT BIOMED ENGN CHUNGLI 32023 TAIWAN TAIPEI MUNICIPAL CHUNG HSIAO HOSP,DEPT OPHTHALMOL TAIPEI TAIWAN
Titolo Testata:
Clinical hemorheology
fascicolo: 5, volume: 15, anno: 1995,
pagine: 775 - 782
SICI:
0271-5198(1995)15:5<775:EOANOH>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
DIABETES-MELLITUS; ERYTHROCYTE FILTERABILITY; RED; DEFORMABILITY; FILTRATION; RHEOLOGY; MICROCIRCULATION; VISCOSITY; PRODUCTS; CELLS;
Keywords:
BLOOD RHEOLOGY; RETINAL MICROCIRCULATION; RED CELL DEFORMABILITY; FEMALE NIDDM; ALPHA-TOCOPHEROL NICOTINATE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
T.W. Chung et al., "EFFECTS OF ALPHA-TOCOPHEROL NICOTINATE ON HEMORHEOLOGY AND RETINAL CAPILLARY BLOOD-FLOW IN FEMALE NIDDM WITH RETINOPATHY", Clinical hemorheology, 15(5), 1995, pp. 775-782

Abstract

The effects of alpha tocopherol nicotinate on hemorheological properties and retinal microcirculation in non-insulin dependent diabetes mellitus (NIDDM) were investigated. Seven female NIDDM with retinopathy orally administered a tocopherol nicotinate at 300 mg after each meal (i.e., 900 mg/day) for a 3 month period. The treatment with the medicine resulted in a significant improvement in blood viscosity at different tested shear rates (P<0.05 or better), red cell deformability (P<0.01) and retinal capillary blood flow velocity (P<0.05), but not in plasma viscosity and red cell rigidity. This study suggests that treatmentfemale NIDDM with alpha - tocopherol nicotinate can improve red cell membrane theological properties and, consequently, improve retinal capillary blood now. Therefore, the treatment may be useful in decelerating the deterioration of retinopathy in NIDDM patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 09:32:27