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OPAC HELP

Titolo:
UPDATE ON CHILDHOOD IMMUNIZATION
Autore:
KRAISINGER M;
Indirizzi:
FLORIDA HOSP MED CTR,DEPT PHARM,601 E ROLLINS ST ORLANDO FL 32803 DUQUESNE UNIV,MYLAN SCH PHARM PITTSBURGH PA 15219
Titolo Testata:
American journal of health-system pharmacy
fascicolo: 6, volume: 55, anno: 1998,
pagine: 563 - 569
SICI:
1079-2082(1998)55:6<563:UOCI>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACELLULAR PERTUSSIS-VACCINE; CONTROLLED TRIAL; UNITED-STATES;
Keywords:
AMERICAN ACADEMY OF FAMILY PHYSICIANS; AMERICAN ACADEMY OF PEDIATRICS; CENTERS FOR DISEASE CONTROL AND PREVENTION; COMBINED THERAPY; DIPHTHERIA AND TETANUS TOXOIDS AND PERTUSSIS VACCINES; DOSAGE SCHEDULES; DRUG ADMINISTRATION ROUTES; IMMUNIZATION; ORGANIZATIONS; PEDIATRICS; POLIO VACCINES; PROTOCOLS; TOXICITY; UNITED STATES; UNITED STATES PUBLIC HEALTH SERVICE; VACCINES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
M. Kraisinger, "UPDATE ON CHILDHOOD IMMUNIZATION", American journal of health-system pharmacy, 55(6), 1998, pp. 563-569

Abstract

Changes made in 1997 and 1998 in the U.S. childhood immunization schedule are discussed, with a focus on the use of poliovirus, pertussis, and combination vaccines. Oral poliovirus vaccine (OPV), the vaccine of choice for all four doses in the polio immunization series since 1962, can cause vaccine-associated paralytic poliomyelitis (VAPP). The inactivated poliovirus vaccine (IPV) has not been associated with VAPP but must be administered by injection and provides inferior intestinal immunity. With the reduced threat of poliovirus importation into the United States, the risk of VAPP, although low, has become less acceptable. The Centers for Disease Control and Prevention accordingly recommended a shift from OPV to IPV in the childhood immunization schedule for the United States, effective January 1997. A sequential OPV and IPV series is recommended, but the schedule includes an OPV-only option, which may be preferred in order to avoid the required injections, and an IPV-only option, which is recommended for immunocompromised persons and their contacts. Concern over local and systemic reactions associated with whole-cell pertussis vaccines, in addition to controversy overa possible relationship between the whole-cell vaccine and neurologicdamage, has led to the development of new diphtheria and tetanus toxoids and acellular pertussis vaccine products for use in the diphtheriaand tetanus toxoids and pertussis immunization series. Several combination products were licensed in 1997, and more are on the way. This will mean fewer inoculations for children. Increased use of IPV and acellular pertussis products could reduce the frequency of VAPP due to OPVand local and systemic reactions associated with whole-cell pertussisvaccine.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 20:23:39