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Titolo:
CLINICAL SEIZURE LATERALIZATION IN MESIAL TEMPORAL-LOBE EPILEPSY - DIFFERENCES BETWEEN PATIENTS WITH UNITEMPORAL AND BITEMPORAL INTERICTAL SPIKES
Autore:
SERLES W; PATARAIA E; BACHER J; OLBRICH A; AULL S; LEHRNER J; LEUTMEZER F; DEECKE L; BAUMGARTNER C;
Indirizzi:
UNIV VIENNA,NEUROL KLIN,WAHRINGER GURTEL 18-20 A-1090 VIENNA AUSTRIA UNIV VIENNA,NEUROL KLIN A-1090 VIENNA AUSTRIA
Titolo Testata:
Neurology
fascicolo: 3, volume: 50, anno: 1998,
pagine: 742 - 747
SICI:
0028-3878(1998)50:3<742:CSLIMT>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
COMPLEX PARTIAL SEIZURES; EPILEPTIFORM DISCHARGES; HEAD; EEG; RELIABILITY; LOBECTOMY; JUDGMENTS; FEATURES; ORIGIN; SIGN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
39
Recensione:
Indirizzi per estratti:
Citazione:
W. Serles et al., "CLINICAL SEIZURE LATERALIZATION IN MESIAL TEMPORAL-LOBE EPILEPSY - DIFFERENCES BETWEEN PATIENTS WITH UNITEMPORAL AND BITEMPORAL INTERICTAL SPIKES", Neurology, 50(3), 1998, pp. 742-747

Abstract

Objective: To compare the reliability of clinical seizure lateralization in temporal lobe epilepsy patients with unitemporal and bitemporalindependent interictal spikes and unilateral hippocampal atrophy or sclerosis (HAMS) on MRI scan. Patients and methods: We studied 11 patients with unitemporal and 10 patients with bitemporal interictal spikes. We calculated a spike ratio by dividing the number of spikes ipsilateral to the side of HAMS by those occurring contralaterally. Results: Clinical seizure lateralization was correct, i.e., ipsilateral to the side of HAMS, significantly more often in the unitemporal group. Spikeratios were significantly higher in seizures that were lateralized correctly as compared with both incorrectly and nonlateralized seizures. Within the individual patients, a significant positive correlation between spike ratios and the proportion of correctly lateralized seizures was found. We identified three categories of symptoms according to lateralization accuracy. Category 1 symptoms (version, postictal paresis, and early ictal vomiting/retching) lateralized to the side of HAMS in 100% of patients in the uni- and bitemporal groups. Category 2 symptoms (dystonic posturing, mouth deviation, postictal dysnomia/dysphasia, and ictal speech) provided a 100% correct lateralization in the unitemporal but not in the bitemporal patients. Category 3 symptoms (nonversive early head turning and unilateral upper extremity automatisms) yielded erroneous lateralization in both patient groups. Conclusions: We conclude that reliable clinical seizure lateralization in mesial temporal lobe epilepsy can only be achieved in patients with unitemporalinterictal spikes, whereas clinical lateralization in patients with bitemporal spikes must be viewed cautiously.

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Documento generato il 17/09/19 alle ore 23:31:21