Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
SALICYLATE AND QUININE SELECTIVELY INCREASE SPONTANEOUS FIRING RATES IN SECONDARY AUDITORY-CORTEX
Autore:
EGGERMONT JJ; KENMOCHI M;
Indirizzi:
UNIV CALGARY,DEPT PHYSIOL & BIOPHYS,2500 UNIV DR NW CALGARY AB T2N 1N4 CANADA UNIV CALGARY,DEPT PSYCHOL CALGARY AB T2N 1N4 CANADA
Titolo Testata:
Hearing research
fascicolo: 1-2, volume: 117, anno: 1998,
pagine: 149 - 160
SICI:
0378-5955(1998)117:1-2<149:SAQSIS>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
INFERIOR COLLICULUS; COCHLEAR NUCLEUS; CAT; TINNITUS;
Keywords:
CAT; PRIMARY AUDITORY CORTEX; ANTERIOR AUDITORY FIELD; SECONDARY AUDITORY CORTEX; MULTIUNIT RECORDING; SPONTANEOUS FIRING RATE; SALICYLATE; QUININE; TINNITUS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
J.J. Eggermont e M. Kenmochi, "SALICYLATE AND QUININE SELECTIVELY INCREASE SPONTANEOUS FIRING RATES IN SECONDARY AUDITORY-CORTEX", Hearing research, 117(1-2), 1998, pp. 149-160

Abstract

This study presents firing rates for simultaneously recorded spontaneous and stimulus driven multi-unit activity in primary auditory cortex(AI), anterior auditory field (AAF) and secondary auditory cortex (AII) in cats before and after application of salicylate or quinine. From21 cats, in three cortical areas simultaneously, a total of 1533 multi-unit files were obtained. The data suggest (1) that both salicylate and quinine significantly increase spontaneous firing rates in AII, whereas in AI and AAF both quinine and salicylate reduced the spontaneous rate; (2) the effect of both drugs was to increase spontaneous ratesfor recording sites with high characteristic frequency (CF) and a tendency to decrease them for low CF sites; (3) the mean stimulus driven firing rates were not affected by either drug except for a decrease produced by quinine in AI; (4) changes in driven firing rate were positively correlated with changes in spontaneous firing rates. This suggests that tinnitus inducing agents selectively increase spontaneous firing rates in the extralemniscal pathway. (C) 1998 Elsevier Science B.V.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 02:13:07