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Titolo:
TOXIC PERIPHERAL NEUROPATHY OF CHICKS FED SENNA-OCCIDENTALIS SEEDS
Autore:
CALORE EE; CAVALIERE MJ; HARAGUCHI M; GORNIAK SL; DAGLI MLZ; RASPANTINI PC; CALORE NMP; WEG R;
Indirizzi:
UNIV SAO PAULO,FAC MED,DEPT PATHOL,LAB MOL PATHOL SAO PAULO BRAZIL EMILIO RIBAS INST,SECT PATHOL SAO PAULO BRAZIL ADOLFO LUTZ INST,SECT PATHOL SAO PAULO BRAZIL INST BIOL,DIV ANIM BIOL,PHARMACOL SECT SAO PAULO BRAZIL UNIV SAO PAULO,FAC VET MED & ZOOTECHNY,DEPT PATHOL SAO PAULO BRAZIL
Titolo Testata:
Ecotoxicology and environmental safety
fascicolo: 1, volume: 39, anno: 1998,
pagine: 27 - 30
SICI:
0147-6513(1998)39:1<27:TPNOCF>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
CASSIA-OCCIDENTALIS; KARWINSKIA-HUMBOLDTIANA; LEG CAES; INTOXICATION; CATTLE;
Keywords:
SENNA OCCIDENTALIS; TOXIC PLANTS; MITOCHONDRIA; TOXIC NEUROPATHIES; PERIPHERAL NEUROPATHIES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
E.E. Calore et al., "TOXIC PERIPHERAL NEUROPATHY OF CHICKS FED SENNA-OCCIDENTALIS SEEDS", Ecotoxicology and environmental safety, 39(1), 1998, pp. 27-30

Abstract

Plants of the genus Senna (formerly Cassia) are poisonous to livestock and other laboratory animals, leading to a syndrome of a widespread muscle degeneration, incoordination, recumbence: and death, The main histologic lesion is necrosis of skeletal muscle fibers, Recently, a mitochondrial myopathy with ragged-red and cytochrome oxidase (COX)-negative muscle fibers was recognized in hens chronically intoxicated withparts of seeds of S. occidentalis. The purpose of the present work was to investigate if there was peripheral nerve involvement in the acute intoxication of chicks with S. occidentalis seeds, Teasing of individual fibers revealed signs of extensive axonal damage with myelin ovoids, Ultrathin sections confirmed the axonal damage, Axons were filled with membranes, some residual disorganized filaments, and enlarged mitochondria, In some instances the axon disappeared and there was secondary degeneration of the myelin sheath, The present work is the first description of the neurotoxic effect of S. occidentalis intoxication. Future work should attempt to determine the mechanisms involved in thisneuropathy. (C) 1998 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/02/20 alle ore 14:30:38