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Titolo:
MAGNETIZATION-TRANSFER CONTRAST - EXPERIM ENTAL SEQUENCE OPTIMIZATIONFOR STUDIES ON CEREBRAL WHITE-MATTER
Autore:
HAHNEL S; HEILAND S; JANSEN O; FREUND M; SARTOR K;
Indirizzi:
UNIV HEIDELBERG,ABT NEURORADIOL,NEUENHEIMER FELD 400 D-69120 HEIDELBERG GERMANY
Titolo Testata:
RoFo. Fortschritte auf dem Gebiete der Rontgenstrahlen und der neuenbildgebenden Verfahren
fascicolo: 2, volume: 168, anno: 1998,
pagine: 185 - 190
SICI:
0936-6652(1998)168:2<185:MC-EES>2.0.ZU;2-1
Fonte:
ISI
Lingua:
GER
Soggetto:
MULTIPLE-SCLEROSIS; MR; LESIONS; IMAGES; DESIGN; BRAIN;
Keywords:
MAGNETIC RESONANCE TRANSFER CONTRAST; CEREBRAL WHITE MATTER IMAGING; MAGNETIZATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
S. Hahnel et al., "MAGNETIZATION-TRANSFER CONTRAST - EXPERIM ENTAL SEQUENCE OPTIMIZATIONFOR STUDIES ON CEREBRAL WHITE-MATTER", RoFo. Fortschritte auf dem Gebiete der Rontgenstrahlen und der neuenbildgebenden Verfahren, 168(2), 1998, pp. 185-190

Abstract

Purpose: A new application for magnetization transfer (MT) MR imagingis the investigation of cerebral white matter. For that a pure Mi effect is desirable. Our purpose was the optimization and testing of an MT sequence for investigations of cerebral white matter. Material and methods: Experimental investigations were performed in phantom materialand in 5 wistar rats using various frequency offsets (FO) (200 Hz-30 000 Hz). Relative signal suppression (rSS) for the phantom material and for callosal white matter of the rat was calculated. The optimized sequence was tested in 25 healthy volunteers. Results: A relatively pure MT effect was achieved with FO > 4000 Hz. rSS for cerebral white matter structures was generally higher than rSS Mr cerebral gray matter structures. rSS for cerebral white matter structures ranged from 45-50%. Conclusion: We present a fast MT sequence with high rSS for cerebralwhite matter and a relatively pure MT effect. Owing to the high rSS-values we expect that this sequence improves differentiation of cerebral white matter lesions. Because of the confusing variety of MT sequence currently described in the literature we believe that standard parameters should be defined to make published results comparable.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 09:26:49