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Titolo:
EARLY AND LATE SYMPATHETIC ACTIVATION IN HYPERTENSION
Autore:
MANCIA G; DIRIENZO M; GIANNATTASIO C; PARATI G; GRASSI G;
Indirizzi:
OSPED SAN GERARDO,CATTEDRA MED INTERNA 1,VIA DONIZETTI 103 MILAN ITALY IRCCS,ITALIAN AUXOL CTR,DON GNOCCHI FDN,CTR BIOENGN MILAN ITALY UNIV MILAN,IRCCS,DEPT CLIN PHYSIOL & HYPERTENS MILAN ITALY UNIV MILAN,S GERARDO TINTORI HOSP,DEPT INTERNAL MED MONZA ITALY
Titolo Testata:
SCANDINAVIAN CARDIOVASCULAR JOURNAL
, volume: 32, anno: 1998, supplemento:, 47
pagine: 9 - 14
Fonte:
ISI
Lingua:
ENG
Soggetto:
LEFT-VENTRICULAR MASS; BLOOD-PRESSURE; NOREPINEPHRINE TURNOVER; HEMODYNAMIC-RESPONSES; NORMOTENSIVE SUBJECTS; INSULIN-RESISTANCE; HUMANS; HYPERTROPHY; INHIBITION; REFLEX;
Keywords:
ESSENTIAL HYPERTENSION; SYMPATHETIC NERVOUS SYSTEM; OBESITY; CARDIOVASCULAR RISK FACTORS; END ORGAN DAMAGE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
40
Recensione:
Indirizzi per estratti:
Citazione:
G. Mancia et al., "EARLY AND LATE SYMPATHETIC ACTIVATION IN HYPERTENSION", SC CARDIOVA, 32, 1998, pp. 9-14

Abstract

In several experimental animal models of hypertension, sympathetic factors have been shown to be involved in the development and/or maintenance of high blood pressure. Although the information available on this issue in man is more scarce, recent evidence clearly indicates the participation of adrenergic mechanisms in the early and late phases of the hypertensive process. In addition, several cardiovascular risk factors frequently associated with hypertension, such as obesity, insulin-resistance, cigarette smoking, and the atherogenic process, are also characterized by alterations in sympathetic cardiovascular drive. Thiscontributes to a further activation of the sympathetic nervous systemthus favoring the development of the end organ damage (e.g. cardiac and vascular hypertrophy) associated with the hypertensive state.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 10:32:20