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Titolo:
TRANSPOSASE BINDING-SITE METHYLATION IN THE EPIGENETICALLY INACTIVATED AC DERIVATIVE DS-CY
Autore:
WANG LH; KUNZE R;
Indirizzi:
UNIV MUNICH,INST GENET & MIKROBIOL,MARIA WARD STR 1A D-80638 MUNICH GERMANY UNIV MUNICH,INST GENET & MIKROBIOL D-80638 MUNICH GERMANY
Titolo Testata:
Plant journal
fascicolo: 4, volume: 13, anno: 1998,
pagine: 577 - 582
SICI:
0960-7412(1998)13:4<577:TBMITE>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
ELEMENT ACTIVATOR AC; TRANSGENIC TOBACCO PLANTS; ZEA-MAYS-L; SUBTERMINAL SEQUENCES; MOLECULAR ANALYSIS; MAIZE; TRANSCRIPTION; REPLICATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
28
Recensione:
Indirizzi per estratti:
Citazione:
L.H. Wang e R. Kunze, "TRANSPOSASE BINDING-SITE METHYLATION IN THE EPIGENETICALLY INACTIVATED AC DERIVATIVE DS-CY", Plant journal, 13(4), 1998, pp. 577-582

Abstract

The authors have determined the C-methylation pattern of the non-autonomous transposable element Ds-cy, which is an epigenetically inactivated, transcriptionally silent derivative of the maize Activator (Ac) element. Like Ac, Ds-cy is hypermethylated at the 3'-end. However, in Ds-cy the 5'-end is also hypermethylated, including all subterminal binding sites for the Ac-encoded transposase protein. As Ds-cy transposesin the presence of an active Ac in the genome, the authors conclude that methylation of the 5'-end TPase binding sites does not interfere with transposition, but correlates with inactivity of the Ac promoter. The authors discuss the implications of these results for the chromatid selectivity of Ac/Ds transposition and the mechanism of Ac-induced chromosome breakage events.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 06:42:05