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Titolo:
RHEOLOGICAL CHANGES IN HYPERTENSIVE PATIENTS TREATED WITH RAMIPRIL
Autore:
ROSENSON RS; HAFNER JM;
Indirizzi:
RUSH PRESBYTERIAN ST LUKES MED CTR,PREVENT CARDIOL CTR,1725 W HARRISON ST CHICAGO IL 60612 RUSH PRESBYTERIAN ST LUKES MED CTR,LIPOPROT & HEMORHEOL RES FACIL,CARDIOL SECT CHICAGO IL 60612
Titolo Testata:
Clinical hemorheology and microcirculation
fascicolo: 1, volume: 17, anno: 1997,
pagine: 41 - 46
SICI:
1386-0291(1997)17:1<41:RCIHPT>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
WHOLE-BLOOD VISCOSITY; SYSTEMIC HYPERTENSION; CARDIAC-HYPERTROPHY; HEALTHY-VOLUNTEERS; FILTERABILITY; ADULTS; CELLS;
Keywords:
BLOOD VISCOSITY; PLASMA VISCOSITY; FIBRINOGEN; HYPERTENSION; RHEOLOGY; RAMIPRIL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
R.S. Rosenson e J.M. Hafner, "RHEOLOGICAL CHANGES IN HYPERTENSIVE PATIENTS TREATED WITH RAMIPRIL", Clinical hemorheology and microcirculation, 17(1), 1997, pp. 41-46

Abstract

This study was designed to characterize blood viscosity changes in 13patients with mild to moderate diastolic hypertension treated with ramipril monotherapy for three months. The ramipril dose was titrated from 2.5 to 20 mg daily to achieve a diastolic blood pressure of less than 90 mm Hg. All patients received a stable dose of ramipril for threemonths. Viscosity measurements were made at 37 degrees C with the Mettler Contraves LS-40 microviscometer. Fibrinogen was determined by theClauss method by averaging three separately acquired plasma samples. The systolic blood pressure (mean +/- standard deviation) was lowered from 141.2+/-9.1 to 129.2+/-11.2 mm Hg (p = 0.005) and the diastolic blood pressure was lowered from 95.2+/-4.9 to 84.2+/-7.3 mm Hg (p = 0.0001). In 13 patients with mild to moderate diastolic hypertension, blood pressure reduction with ramipril was accompanied by no significant changes in blood viscosity, plasma viscosity, serum viscosity or fibrinogen.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/10/20 alle ore 06:20:11