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Titolo:
ULTRASONIC MYOCARDIAL TEXTURE IN HYPERTENSIVE MILD-TO-MODERATE LEFT-VENTRICULAR HYPERTROPHY - A VIDEODENSITOMETRIC STUDY
Autore:
DIBELLO V; PEDRINELLI R; BIANCHI M; GIORGI D; BERTINI A; VALENTI G; GHIONE S; CORCHIA A; DELLOMO G; PATERNI M; GIUSTI C;
Indirizzi:
UNIV PISA,IST CLIN MED 2,VIA ROMA 67 I-56100 PISA ITALY UNIV PISA,IST CLIN MED 1 I-56100 PISA ITALY CNR,IST FISIOL CLIN PISA ITALY
Titolo Testata:
American journal of hypertension
fascicolo: 2, volume: 11, anno: 1998,
pagine: 155 - 164
SICI:
0895-7061(1998)11:2<155:UMTIHM>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
PRESSURE-OVERLOAD HYPERTROPHY; RAT LEFT-VENTRICLE; TWO-DIMENSIONAL ECHOCARDIOGRAPHY; TISSUE CHARACTERIZATION; ARTERIAL-HYPERTENSION; BLOOD-PRESSURE; FIBRILLAR COLLAGEN; CARDIAC CYCLE; GRAY-LEVEL; FIBROSIS;
Keywords:
ECHOCARDIOGRAPHY; HYPERTENSION; VIDEODENSITOMETRIC; ULTRASONIC TISSUE CHARACTERIZATION; AMBULATORY BLOOD PRESSURE MONITORING;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
42
Recensione:
Indirizzi per estratti:
Citazione:
V. Dibello et al., "ULTRASONIC MYOCARDIAL TEXTURE IN HYPERTENSIVE MILD-TO-MODERATE LEFT-VENTRICULAR HYPERTROPHY - A VIDEODENSITOMETRIC STUDY", American journal of hypertension, 11(2), 1998, pp. 155-164

Abstract

Myocardial texture analysis of two-dimensional echocardiographic graylevel distribution is abnormal in hypertensive patients with severe increase of left ventricular mass. The aim of this study was to investigate the behavior of this parameter in hypertensive patients with absent-to-moderate left ventricular hypertrophy, more representative of the overall hypertensive population. We compared male essential hypertensive patients, with absent or mild-to-moderate left ventricular hypertrophy, with normotensive sedentary healthy subjects as controls. The groups (n = 18 each) were age-(+/- 2 years) and sex-matched. All subjects performed ambulatory blood pressure measurements for the evaluationof 24 h mean systolic and diastolic blood pressure. Quantitative analysis of echocardiographic digitized imaging was performed through a calibrated 256 gray level digitization system to;calculate midseptum andmidposterior end-diastolic and end-systolic first and second order textural analysis. In particular were observed the mean gray level cyclic variations to deriving the cyclic variation index (CVI). The hypertensives showed a significantly lower CVI compared with controls both for septum (P < .001) and for posterior wall (P < .0001). No significantrelationships were found between CVI and relative diastolic thicknessboth of septum and posterior wall. Conversely, a significant inverse relationship was found between systolic arterial pressure values and CVI both of septum and posterior wall. Abnormalities of two dimensionalechocardiographic gray level distribution are present also in hypertensive patients with absent or with mild-to-moderate levels of left ventricular hypertrophy, but seem unrelated to the degree of echocardiographic hypertrophy as such. Changes in collagen network distribution ormicrocirculatory alterations, secondary to pressure-volume overload per se or to other complex humoral factors, could explain these abnormalities. Further work is needed to establish the clinical, therapeutic,and prognostic implications of these findings. (C) 1998 American Journal of Hypertension, Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 21:13:10